Recent advances in synthesis of functionalized β-lactams through cyclization of N-propargyl amine/amide derivatives
| Author | Vessally, Esmail |
| Author | Babazadeh, Mirzaagha |
| Author | Hosseinian, Akram |
| Author | Edjlali, Ladan |
| Author | Sreerama, Lakshmaiah |
| Available date | 2024-07-07T11:01:56Z |
| Publication Date | 2018-01-01 |
| Publication Name | Current Organic Chemistry |
| Identifier | http://dx.doi.org/10.2174/1385272821666170519113904 |
| Citation | Vessally, E., Babazadeh, M., Hosseinian, A., Edjlali, L., & Sreerama, L. (2018). Recent advances in synthesis of functionalized β-lactams through cyclization of N-propargyl amine/amide derivatives. Current Organic Chemistry, 22(2), 199-205. |
| ISSN | 13852728 |
| Abstract | β-lactams have attracted a significant attention due to their potential biological activities and wide variety of synthetic applications. Developing novel and efficient methods for construction of functionalized β-lactams has been the subject of a number of papers in recent years. N-Propargyl amines/amides are one of the most specific class of alkynes having diverse reaction patterns. It is well known that they can undergo a number of cyclization reactions to produce various significant nitrogen containing heterocycles. This review surveys literature methods for the synthesis of highly substituted β-lactams from simple and easily available N-propargyl amine/amide derivatives from 1991 to 2017. |
| Language | en |
| Publisher | Bentham Science Publishers B.V. |
| Subject | 4-exo-dig cyclization Carbon monoxide N-propargylamides N-propargylamines Ugi-adducts β-lactams |
| Type | Other |
| Pagination | 199-205 |
| Issue Number | 2 |
| Volume Number | 22 |
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