تصفح College of Pharmacy حسب المؤلف "Munusamy, Shankar"
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PROTECTIVE EFFECTS OF METFORMIN IN AN IN VITRO MODEL OF PROTEINURIC KIDNEY DISEASE
Allouch, Soumaya (2017 , Master Thesis)Albuminuria, a hallmark of chronic kidney disease (CKD), plays a crucial role in the etiology of CKD. High albumin levels are thought to induce endoplasmic reticulum (ER) stress and activate the AKT pathway, and lead to ... -
STANDARDIZATION OF AN IN VITRO MODEL OF DIABETIC NEPHROPATHY IN RENAL TUBULAR CELLS AND INVESTIGATION OF THE ROLE OF ALDOSE REDUCTASE PATHWAY IN HIGH GLUCOSE-INDUCED RENAL CELL INJURY
El Gamal, Heba (2015 , Master Thesis)Diabetic nephropathy (DN) is the leading cause of end stage renal disease, and one of the most serious microvascular complications of diabetes mellitus. Increase in the shift of glucose into the aldose reductase pathway ... -
Synthesis and Pharmacological Evaluation of Different Piperine Analogs for Therapeutic Potential to Prevent ER Stress
Hammad, Ayat Samir (2015 , Master Thesis)Background: Endoplasmic reticulum (ER) is the chief organelle involved in protein folding and maturation. Emerging studies implicate the role of ER stress in the development of chronic kidney disease (CKD). Thus, there is ...