تصفح College of Pharmacy حسب الموضوع "Pharmacology"
السجلات المعروضة 1 -- 2 من 2
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Cathepsin B Induced Cardiomyocyte Hypertrophy Requires Activation of The Na+/H+ Exchanger Isoform-1
(2016 , Master Thesis)Multiple studies have demonstrated that proteases, specifically cathepsin B (Cat B) and matrix metalloproteinase-9 (MMP-9) contribute to the remodeling of the extracellular matrix (ECM), a hallmark of cardiac hypertrophy ... -
PROTECTIVE EFFECTS OF METFORMIN IN AN IN VITRO MODEL OF PROTEINURIC KIDNEY DISEASE
(2017 , Master Thesis)Albuminuria, a hallmark of chronic kidney disease (CKD), plays a crucial role in the etiology of CKD. High albumin levels are thought to induce endoplasmic reticulum (ER) stress and activate the AKT pathway, and lead to ...