تصفح College of Pharmacy حسب النوع "Dissertation"
السجلات المعروضة 1 -- 6 من 6
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Anticancer Activity of Neosetophomone-B, a Fungal Secondary Metabolite, Against Hematological Malignancies
(2023 , Dissertation)Anticancer Activity of Neosetophomone-B, a Fungal Secondary Metabolite, Against Hematological Malignancies downregulation, and p21 and p27 upregulation were observed in NSP-B-treated leukemia, lymphoma, and myeloma cells. ... -
CLINICAL AND ECONOMIC IMPACT OF GENETIC AND NON-GENETIC FACTORS ON INR NORMALIZATION IN PRE-OPERATIVE MANAGEMENT OF WARFARIN PATIENTS
(2021 , Dissertation)The aim of this Ph.D. was to evaluate the periprocedural anticoagulation management of patients receiving warfarin in Qatar clinically and economically. In addition, exploring the clinical and economic impact of genetic ... -
CLINICAL VERSUS FIXED WARFARIN DOSING AND THE ADDED EFFECT OF A GENOTYPE GUIDED ALGORITHM ON WARFARIN DOSE PREDICTION IN ARABS
(2025 , Dissertation)Warfarin prescribing has been a challenge due to the need for frequent monitoring. Commonly, warfarin is prescribed using a fixed warfarin dosing method (FWD). Genotype guide warfarin dosing (GWD) is a method that uses ... -
INVESTIGATING THE ROLE OF THE ARYL HYDROCARBON RECEPTOR AND BCL-2 FAMILY PROTEINS IN OVARIAN CANCER STEM CELLS DEVELOPMENT AND CHEMORESISTANCE
(2024 , Dissertation)Gynecological malignancies are a severe threat to female health. Ovarian Cancer (OC), the most lethal gynecological malignancy, is clinically presented with chemoresistance and a higher relapse rate. This could be endorsed ... -
THE EFFECT OF OBESITY ON RIVAROXABAN PHARMACOKINETICS AND PHARMACODYNAMICS
(2024 , Dissertation)Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a prevalent condition that is associated with high rates of morbidity and mortality worldwide. Similarly, atrial fibrillation ... -
THE MOLECULAR MECHANISMS UNDERPINNING THE ROLE OF SESTRIN 2 IN ENDOTHELIAL FUNCTION
(2025 , Dissertation)Cardiovascular diseases (CVD) associated with diabetes persist to be a major cause of death worldwide. Endothelial dysfunction (ED), a condition characterized by impaired Nitric Oxide (NO) bioavailability in endothelial ...
