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The role of CD44, hyaluronan and NHE1 in cardiac remodeling.
(
Elsevier
, 2018 , Article)
Cardiac remodeling, characterized by excessive extracellular matrix (ECM) remodeling, predisposes the heart to failure if left unresolved. Understanding the signaling mechanisms involved in excessive extracellular matrix ...
Hemodynamic Studies for Analyzing the Teratogenic Effects of Drugs in the Zebrafish Embryo.
(
Humana Press
, 2018 , Book chapter)
Investigations of teratogenic effects of drugs generally involve testing the drug on animals and zebrafish embryo is a commonly used animal model for that purpose. In these studies, cardiovascular function of the animals ...
Immunomodulation Induced by Host Pathogen Interaction
(
Hindawi
, 2019 , Article)
Controlling and preventing infections require deep understanding of the complex interplay that occurs between the host and pathogen following infection. In essence, immunomodulation is any process leading to an immune ...
Viruses and Autoimmunity: A Review on the Potential Interaction and Molecular Mechanisms.
(
MDPI
, 2019 , Article)
For a long time, viruses have been shown to modify the clinical picture of several autoimmune diseases, including type 1 diabetes (T1D), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjögren's syndrome ...
Impact of Physical Exercise on Gut Microbiome, Inflammation, and the Pathobiology of Metabolic Disorders.
(
The Society for Biomedical
, 2019 , Article Review)
The gastrointestinal tract (GIT) harbors a complex and diverse microbial composition that outnumbers our own body cells and their gene contents. These microbes play a significant role in host metabolism and energy homeostasis. ...
Molecular characterization of extended spectrum β -lactamases enterobacteriaceae causing lower urinary tract infection among pediatric population.
(
BioMed Central
, 2018 , Article)
The β-lactam antibiotics have traditionally been the main treatment of Enterobacteriaceae infections, nonetheless, the emergence of species producing β- Lactamases has rendered this class of antibiotics largely ineffective. ...
Antibiotic Resistance Profile of Commensal Escherichia coli Isolated from Broiler Chickens in Qatar.
(
International Association for Food Protection
, 2018 , Article)
Antibiotic resistance (AR) is a growing public health concern worldwide, and it is a top health challenge in the 21st century. AR among Enterobacteriaceae is rapidly increasing, especially in third-generation cephalosporins ...
Detection of Paracetamol as substrate of the gut microbiome
(
University of Karachi, Pharmacy College
, 2019 , Article)
Gut microbiome, a new organ; represent targets to alter pharmacokinetics of orally administered drugs. Recently, in vitro trials endorsed the idea that orally administered drugs interact and some of their quantity may be ...
Seroprevalence of hepatitis E virus among blood donors in Qatar (2013-2016)
(
Wiley
, 2017 , Article)
BACKGROUND
Hepatitis E virus (HEV) is an RNA virus transmitted mainly through zoonotic transmission or fecal–oral route. More than 80% of Qatar's population are expatriates, including many coming from hyperendemic ...
Assessing the burden of intestinal parasites affecting newly arrived immigrants in Qatar
(
BioMed Central
, 2016 , Article)
In the last decades, the enormous influx of immigrants to industrialized countries has led to outbreaks of parasitic diseases, with enteric infections being amongst the most frequently encountered. In its strategy to control ...