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AuthorNasrallah, Gheyath K
AuthorDargham, Soha R
AuthorMohammed, Layla I
AuthorAbu-Raddad, Laith J
Available date2018-02-11T06:21:35Z
Publication Date2018-01-01
Publication NameSexually Transmitted Infectionsen_US
Identifierhttp://dx.doi.org/10.1002/jmv.24916
CitationNasrallah G, Dargham S, Mohammed L, et al P3.84 Estimating the antibody prevalence of herpes simplex virus type 1 among select middle east and north africa populations Sex Transm Infect 2017;93:A124.
ISSN1368-4973
URIhttp://hdl.handle.net/10576/6298
AbstractHSV-1 epidemiology in the Middle East and North Africa (MENA) remains poorly understood. Our study aimed to measure HSV-1 antibody prevalence (seroprevalence) and its age-distribution among select MENA populations residing in Qatar. Sera were collected from male blood donors attending Hamad Medical Corporation 2013-2015. A total of 2,077 sera were tested for anti-HSV-1 antibodies using HerpeSelect® 1 ELISA IgG kits (Focus Diagnostics, Cypress, CA). Robust Poisson regression was conducted to estimate adjusted infection prevalence ratios. Country-specific HSV-1 seroprevalence was estimated for 10 national populations: 97.5% among Egyptians, 92.6% among Yemenis, 90.7% among Sudanese, 88.5% among Syrians, 86.5% among Jordanians, 82.3% among Qataris, 81.4% among Iranians, 81.4% among Lebanese, 80.5% among Palestinians, and 77.0% among Pakistanis. Age-specific HSV-1 seroprevalence was estimated for Egypt, the Fertile Crescent (Iraq, Jordan, Lebanon, Palestine, and Syria), and Qatar. Seroprevalence increased with age among Fertile Crescent and Qatari nationals. Seroprevalence increased from 70.0% among those aged ≤ 24 years up to 98.0% among those aged ≥55 years among Fertile Crescent nationals. Seroprevalence was consistently above 90% for all ages among Egyptians. HSV-1 seroprevalence is high in MENA, though with some variation across countries. The seroprevalence appears to have declined among current young age cohorts compared to its levels a few decades ago.
Languageen
PublisherBMJ Publishing Group
SubjectMiddle East and North Africa
Subjectherpes
Subjectherpes simplex virus type 1
Subjectprevalence
Subjectsexually transmitted infection
TitleEstimating seroprevalence of herpes simplex virus type 1 among different Middle East and North African male populations residing in Qatar.
TypeArticle
Pagination124
Issue Number2
Volume Number93
dc.identifier.essn 1472-3263


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