Central Laboratories Unit: المرسلات الحديثة
السجلات المعروضة 21 -- 40 من 124
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Microwave-aided sensitive and eco-friendly HPTLC method for estimation of mirabegron using NBD-Cl as bio-sensing fluorescent probe by Integration of principal component Analysis, response surface modelling and white analytical chemistry approach
( Elsevier B.V. , 2024 , Article)A large number of analytical methods have been used in in-vivo pharmacokinetic investigations and assays of mirabegron, which is used to treat overactive bladder. Because mirabegron does not give fluorescence, there is no ... -
An Eco-Friendly and Sensitive Microwave-Aided Spectrofluorophotometric Characterization of Mirabegron-Loaded Nanocarriers by Amalgamation of Design of Experiments and White Analytical Chemistry
( John Wiley and Sons , 2024 , Article)Mirabegron, a drug for treatment of overactive bladder, has low water solubility and bioavailability. Researchers used quality by design to develop and characterize second-generation lipid nanocarriers for mirabegron, ... -
Lipid-based nanoparticles: innovations in ocular drug delivery
( Frontiers Media , 2024 , Article Review)Ocular drug delivery presents significant challenges due to intricate anatomy and the various barriers (corneal, tear, conjunctival, blood-aqueous, blood-retinal, and degradative enzymes) within the eye. Lipid-based ... -
Author Correction: Surfactant/organic solvent free single-step engineering of hybrid graphene-Pt/TiO2 nanostructure: Efficient photocatalytic system for the treatment of wastewater coming from textile industries
( Springer Nature , 2019 , Article)A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. -
Carica Papaya leaf-infused metal oxide nanocomposite: a green approach towards water treatment and antibacterial applications
( Springer , 2024 , Article)This study successfully synthesized ZnO–CuO nanocomposite using the hydrothermal method with Carica papaya leaf extract. The incorporation of the leaf extract significantly enhanced the nanocomposite properties, a novel ... -
Role of the intercalated ions on the high capacitance behavior of Ti 3 C 2 Tx MXene nanohybrids
( Taylor and Francis Ltd. , 2023 , Article)Ti3C2Tx (MXene) is prone to surface oxidation because of the presence of oxygen surface terminals in its surfaces. In this work, the effect of oxygen surface terminals has been reduced by replacing it with other surface ... -
Non-covalent functionalization of surfactant-assisted graphene oxide with silver nanocomposites for highly efficient photocatalysis and anti-biofilm applications
( Elsevier , 2024 , Article)This study presents a comprehensive investigation on the synthesis and characterization of surfactant-assisted graphene oxide non-covalent functionalized silver nanocomposites (rGS-AgNPs) for achieving remarkable photocatalytic ... -
Development of novel nanoemulsion of pioglitazone used in the treatment of diabetes and its gel form for the treatment of skin diseases
( Elsevier , 2024 , Article)Pioglitazone (PGL), an antidiabetic drug within the thiazolidinedione class, is utilized in managing type-2-diabetes-mellitus. Additionally, it has been observed to exhibit therapeutic effects on various inflammatory ... -
In-vivo pharmacokinetic study of ibrutinib-loaded nanostructured lipid carriers in rat plasma by sensitive spectrofluorimetric method using harmonized approach of quality by design and white analytical chemistry
( Elsevier , 2024 , Article)Ibrutinib, an antineoplastic agent tackling chronic lymphocytic leukemia, mantle cell lymphoma, and Waldenstrom’s Macroglobulinemia, falls under the category of BCS class II drugs, characterized by a puzzling combination ... -
Targeting protein receptors and enzymes for precision management of urolithiasis: A comprehensive review
( Elsevier , 2024 , Article)Urolithiasis, characterized by the formation of solid crystalline structures within the urinary tract, presents a significant global health burden with high recurrence rates and limited treatment efficacy. Recent research ... -
Ultratrace determination of strontium-90 in environmental soil samples from Qatar by collision/reaction cell-inductively coupled plasma mass spectrometry (CRC-ICP-MS/MS)
( The American Society of Mechanical Engineers (ASME) , 2014 , Conference)Because of the very low level of 90Sr in the environmental soil samples and its determination by beta counting may take several weeks, we developed a procedure for ultratrace determination of 90Sr using collision reaction ... -
A novel mucoadhesive paliperidone-nanoemulsion developed using the ultrasonication method in the treatment of schizophrenia
( Royal Society of Chemistry , 2024 , Article)Aim: To develop paliperidone mucoadhesive-nanoemulsion (PLP-NE) to enhance brain bioavailability. To evaluate comparative effects of PLP-NE and CS-PLP-NE in the treatment of schizophrenia, followed by a toxicity study of ... -
In-Vitro Dissolution Study of Solid Dispersion Adsorbate of Nateglinide by Eco-Friendly Liquid Chromatography-Tandem Mass Spectrometric Method through Harmonized Approach of White Analytical Chemistry and Analytical Quality by Design
( Springer Nature , 2024 , Article)Purpose: Nateglinide, a member of the meglitinide class, is used as an oral antihyperglycemic agent to treat non-insulin-dependent diabetes mellitus. It falls under the BCS class II category and has a low solubility ... -
Eco-friendly green synthesis of silver nanoparticles utilizing olive oil waste by-product and their incorporation into a chitosan-aloe vera gel composite for enhanced wound healing in acid burn injuries
( Elsevier , 2024 , Article)This study focused on the green synthesis of silver nanoparticles (AgNPs) using olive oil waste by-product and their incorporation into Chitosan-Aloe-Vera gel (AgNPs/AV-CS gel). The synthesized AgNPs exhibited a hydrodynamic ... -
Integrated approach of white analytical chemistry and design of experiments to microwave-assisted sensitive and eco-friendly spectrofluorimetric estimation of mirabegron using 4-chloro-7-nitrobezofuran as biosensing fluorescent probe
( Elsevier , 2024 , Article)The USFDA recently approved mirabegron, a novel once-daily β-3 adrenoceptor agonist for oral administration, as a transformative treatment for overactive bladder. Despite the existence of numerous analytical methods for ... -
Significance of Triazole in Medicinal Chemistry: Advancement in Drug Design, Reward and Biological Activity.
( Wiley , 2024 , Article Review)One of the triazole tautomers, 1,2,4-triazole derivatives, has a wide range of biological activities that suggest its potential therapeutic utility in medicinal chemistry. These actions include anti-inflammatory, anti-cancer, ... -
The effect of graphene on the activation energy of grain growth for the nanocrystalline thermoelectric n-type Bi2Te2.7Se0.3
( Springer Nature , 2022 , Article)Even though bismuth telluride is frequently produced by mechanical alloying for thermoelectric materials, no data has been published addressing the thermal behavior and activation energy of the milled n-type Bi2Te2.7Se0.3 ... -
Process optimization and method validation for efficient valorization of low- grade coal into humic substances
( Elsevier , 2024 , Article)The exploration of low-grade coal resources and progress in the extraction method of humic substances are the core aims of this study. Ultrasonic and microwave assisted alkali extractions were compared with conventional ... -
Polyolefin-Based Smart Self-Healing Composite Coatings Modified with Calcium Carbonate and Sodium Alginate.
( MDPI , 2024 , Article)Corrosion-related damage incurs significant capital costs in many industries. In this study, an anti-corrosive pigment was synthesized by modifying calcium carbonate with sodium alginate (SA), and smart self-healing coatings ... -
Investigation on the effect of several parameters involved in the biodegradation of polyethylene (PE) and low-density polyethylene (LDPE) under various seawater environments
( Elsevier , 2024 , Article)This work investigates the biodegradation of polyethylene (PE) and low-density polyethylene (LDPE) and the leaching of their harmful additives. Micro/macro-plastics of both types were subjected to different laboratory-controlled ...
