• English
    • العربية
  • العربية
  • Login
  • QU
  • QU Library
  •  Home
  • Communities & Collections
  • Help
    • Item Submission
    • Publisher policies
    • User guides
    • FAQs
  • About QSpace
    • Vision & Mission
View Item 
  •   Qatar University Digital Hub
  • Qatar University Institutional Repository
  • Academic
  • University Publications
  • QU Ceased Journals
  • Qatar University Science Journal - [From 1981 TO 2007]
  • View Item
  • Qatar University Digital Hub
  • Qatar University Institutional Repository
  • Academic
  • University Publications
  • QU Ceased Journals
  • Qatar University Science Journal - [From 1981 TO 2007]
  • View Item
  •      
  •  
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    An early marker of monoclonal light chain protein In bladder cancer

    Thumbnail
    View/Open
    079414s-0008-fulltext.pdf (326.9Kb)
    Date
    1994
    Author
    Ibrahim, A. M. [ا م ابراهيم]
    Khalil, A. M.
    Shaheen, F. A.
    Hussein, M. M.
    El-Shawarby, N. K.
    Metadata
    Show full item record
    Abstract
    Bladder cancer complicating schistosomiasis is a major cause of cancer mortality in Egypt. It affects farmers who suffer from repeated and severe chronic schistosomal cystitis. The late presentation of this disease is probably due to the overlapping and similar symptoms of simple bilharzial cystitis and bladder carcinoma. The present work deals with study of the variation of low molecular weight proteins, immunoprotein-patterns present in both serum and urine in different groups of bladder cancer patients in an attempt for predicting and screening the early and late stages of bladder carcinoma. The increased urinary excretion of high molecular weight proteins, the immunoglobulins (IgA, IgM, IgG) especially IgG and low molecular weight proteins such as light chain protein of kappa (K) as well as B-2-microglobulin demonstrated in our patients of bladder carcinomas in the present study may be caused by the admixture of proteins to urine from tumour surface. The increased level of IgG type kappa in urine could also be related to the high degree of plasma cell infiltration usually associated with bladder tumours, or it may be due to alteration in the genetic material present in the chromosomes of the nucleic acid components of cells which is the basis for their transformation into neoplasms. On conclusion, our results demonstrated that detection of monoclonal light chain proteins can be used for diagnosis and predicting the early or late stages of the disease and its different pathological types.
    DOI/handle
    http://hdl.handle.net/10576/9852
    Collections
    • Qatar University Science Journal - [From 1981 TO 2007] [‎770‎ items ]

    entitlement


    Qatar University Digital Hub is a digital collection operated and maintained by the Qatar University Library and supported by the ITS department

    Contact Us | Send Feedback
    Contact Us | Send Feedback | QU

     

     

    Home

    Submit your QU affiliated work

    Browse

    All of Digital Hub
      Communities & Collections Publication Date Author Title Subject Type Language Publisher
    This Collection
      Publication Date Author Title Subject Type Language Publisher

    My Account

    Login

    Statistics

    View Usage Statistics

    About QSpace

    Vision & Mission

    Help

    Item Submission Publisher policiesUser guides FAQs

    Qatar University Digital Hub is a digital collection operated and maintained by the Qatar University Library and supported by the ITS department

    Contact Us | Send Feedback
    Contact Us | Send Feedback | QU

     

     

    Video