Browsing by Author "Alkilany, Alaaldin"
Now showing items 1-8 of 8
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Can we use normal saline stored under stress conditions? A simulated prehospital emergency medical setting
( Elsevier Ltd , 2023 , Article)Background: Data on stability and suitability to use normal saline stored under stress conditions in ambulances is lacking. Objective: We aimed to study the impact of exposure to extreme temperature variations on normal ... -
Comprehensive evaluation of the pharmacological and toxicological effects of γ-valerolactone as compared to γ-hydroxybutyric acid: Insights from in vivo and in silico models
( Elsevier , 2023 , Article)Γ-valerolactone (GVL), marketed online as “Tranquilli-G” and “excellent Valium”, is used as a legal substitute for γ-hydroxybutyric acid (GHB); however, until now, GVL has only been connected to one Drug-Facilitated Sexual ... -
Doxorubicin conjugates: a practical approach for its cardiotoxicity alleviation
( Taylor & Francis , 2024 , Article)Introduction: Doxorubicin (DOX) emerges as a cornerstone in the arsenal of potent chemotherapeutic agents. Yet, the clinical deployment of DOX is tarnished by its proclivity to induce severe cardiotoxic effects, culminating ... -
Dual-loaded liposomal carriers to combat chemotherapeutic resistance in breast cancer
( Taylor & Francis , 2024 , Article)Introduction: The resistance to chemotherapy is a significant hurdle in breast cancer treatment, prompting the exploration of innovative strategies. This review discusses the potential of dual-loaded liposomal carriers to ... -
Eutectics in Pharmacy Curriculum: A Simple Demonstration with Pharmaceutical Relevance
( ACS Publications , 2023 , Article)In chemistry, a eutectic mixture refers to a mixture of two or more components at which the lowest possible freezing point is observed. This phenomenon is covered in a wide range of curricula such as physics, chemistry, ... -
Quality by Design Approach in Liposomal Formulations: Robust Product Development
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Nanomedicine is an emerging field with continuous growth and differentiation. Liposomal formulations are a major platform in nanomedicine, with more than fifteen FDA-approved liposomal products in the market. However, as ... -
The synthetic cathinones MDPHP and MDPV: Comparison of the acute effects in mice, in silico ADMET profiles and clinical reports
( Elsevier , 2024 , Article)The 3,4-methylenedioxy-alpha-pyrrolidinohexanophenone (MDPHP) is a synthetic cathinone closely related to 3,4-methylenedioxypyrovalerone (MDPV), one of the most common synthetic cathinones present in the “bath salts”. MDPHP ... -
Utilization of the Transparent Peer Review Policy to Train Graduate Pharmacy Students on Scientific Critique
( Elsevier , 2024 , Article)ObjectiveRecognizing the importance of training graduate students in scientific critique and peer review, we introduced an innovative instructional strategy using the transparent peer review policy (TPRP). This study aimed ...
