Browsing by Author "Mechref, Yehia"
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Exploring serum glycome patterns after moderate to severe traumatic brain injury: A prospective pilot study
Stefania, Mondello; Sandner, Viktor; Goli, Mona; Czeiter, Endre; Amrein, Krisztina; Kochanek, Patrick M.; Gautam, Sakshi; Cho, Byeong Gwan; Morgan, Ryan; Nehme, Ali; Fiumara, Giacomo; Eid, Ali H.; Barsa, Chloe; Haidar, Muhammad Ali; Buki, Andras; Kobeissy, Firas H.; Mechref, Yehia... more authors ... less authors ( Elsevier , 2022 , Article)BackgroundGlycans play essential functional roles in the nervous system and their pathobiological relevance has become increasingly recognized in numerous brain disorders, but not fully explored in traumatic brain injury ... -
High fat diet exacerbates long-term metabolic, neuropathological, and behavioral derangements in an experimental mouse model of traumatic brain injury
Stanley, Ibeh; Bakkar, Nour-Mounira Z.; Ahmad, Fatima; Nwaiwu, Judith; Barsa, Chloe; Mekhjian, Sarine; Reslan, Mohammad Amine; Eid, Ali H.; Harati, Hayat; Nabha, Sanaa; Mechref, Yehia; El-Yazbi, Ahmed F.; Kobeissy, Firas... more authors ... less authors ( Elsevier , 2023 , Article)AimsTraumatic brain injury (TBI) constitutes a serious public health concern. Although TBI targets the brain, it can exert several systemic effects which can worsen the complications observed in TBI subjects. Currently, ... -
Inflammasomes as biomarkers and therapeutic targets in traumatic brain injury and related-neurodegenerative diseases: A comprehensive overview
Dania, Kattan; Barsa, Chloe; Mekhijian, Sarin; Shakkour, Zaynab; Jammoul, Maya; Doumit, Mark; Zabala, Maria Camila Pareja; Darwiche, Nadine; Eid, Ali H.; Mechref, Yehia; Wang, Kevin K.; de Rivero Vaccari, Juan Pablo; Munoz Pareja, Jennifer C.; Kobeissy, Firas... more authors ... less authors ( Elsevier , 2023 , Article)Given the ambiguity surrounding traumatic brain injury (TBI) pathophysiology and the lack of any Food and Drug Administration (FDA)-approved neurotherapeutic drugs, there is an increasing need to better understand the ... -
Mitoquinone supplementation alleviates oxidative stress and pathologic outcomes following repetitive mild traumatic brain injury at a chronic time point
Maha, Tabet; El-Kurdi, Marya; Haidar, Muhammad Ali; Nasrallah, Leila; Reslan, Mohammad Amine; Shear, Deborah; Pandya, Jignesh D.; El-Yazbi, Ahmed F.; Sabra, Mirna; Mondello, Stefania; Mechref, Yehia; Shaito, Abdullah; Wang, Kevin K.; El-Khoury, Riyad; Kobeissy, Firas... more authors ... less authors ( Elsevier , 2022 , Article)Traumatic brain injury (TBI) is a major cause of disability and death. Mild TBI (mTBI) constitutes ~75% of all TBI cases. Repeated exposure to mTBI (rmTBI), leads to the exacerbation of the symptoms compared to single mTBI. ... -
Unveiling a Biomarker Signature of Meningioma: the Need for a Panel of Genomic, Epigenetic, Proteomic, and RNA Biomarkers to Advance Diagnosis and Prognosis
Halabi, Reem; Dakroub, Fatima; Haider, Mohammad Z.; Patel, Stuti; Amhaz, Nayef A.; Reslan, Mohammad A.; Eid, Ali H.; Mechref, Yehia; Darwiche, Nadine; Kobeissy, Firas H.; Omeis, Ibrahim; Shaito, Abdullah... more authors ... less authors ( preprints , 2023 , Preprint)Meningiomas are the most prevalent primary intracranial tumors. The majority are benign but can undergo dedifferentiation in grades classified from I to III. Meningiomas tremendous variability in tumor behavior and slow ...