Browsing by Author "Rizeq, Balsam"
Now showing items 1-5 of 5
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Dasatinib and PD-L1 inhibitors provoke toxicity and inhibit angiogenesis in the embryo
Maha, Al-Asmakh; Bawadi, Hiba; Hamdan, Munia; Gupta, Ishita; Kheraldine, Hadeel; Jabeen, Ayesha; Rizeq, Balsam; Al Moustafa, Ala-Eddin... more authors ... less authors ( Elsevier , 2021 , Article)Dasatinib is a targeted cancer therapy, while programmed death ligand 1 (PD-L1) inhibitors are a form of immune checkpoint therapy used to treat various types of cancers. Several studies showed the potential efficacy of ... -
Novel CD44-downstream signaling pathways mediating breast tumor invasion
Ouhtit, Allal; Rizeq, Balsam; Abou Saleh, Haissam; Rahman, MD Mizanur; Zayed, Hatem ( Ivyspring International Publisher , 2018 , Article Review)CD44, also known as homing cell adhesion molecule is a multi-structural cell molecule involved in cell-cell and cell-extracellular matrix communications. CD44 regulates a number of central signaling pathways, including ... -
Plasmonic MXene-based nanocomposites exhibiting photothermal therapeutic effects with lower acute toxicity than pure MXene
Hussein, Essraa; Zagho, Moustafa; Rizeq, Balsam; Younes, Nadin; Pintus, Gianfranco; Mahmoud, Khaled; Nasrallah, Gheyath; Elzatahry, Ahmed... more authors ... less authors ( DOVE Medical Press , 2019 , Article)Purpose: Here, we fabricated two plasmonic 2D Ti3C2Tx-based nanocomposites (Au/MXene and Au/Fe3O4/MXene) with similarly high anti-cancer photothermal therapy (PTT) capabilities, but with less in vivo toxicity than a pure ... -
The Role of CCL21/CCR7 Chemokine Axis in Breast Cancer Progression
Malki, Mohammed Imad; Rizeq, Balsam ( MDPI , 2015 , Article Review)Tumor-induced lymphangiogenesis facilitates breast cancer progression by generating new lymphatic vessels that serve as conduits for tumor dissemination to lymph nodes and beyond. Given the recent evidence suggesting the ... -
Towards understanding the mechanisms of actions of carcinoembryonic antigen-related cell adhesion molecule 6 in cancer progression
Rizeq, Balsam; Zakaria, Zain; Ouhtit, Allal ( Wiley Open Access , 2017 , Article Review)Human carcinoembryonic antigen (CEA) is the prototypic member of a family of highly related cell surface glycoproteins that includes carcinoembryonic antigenrelated cell adhesion molecule 6 (CEACAM6) and others. CEACAM6 ...