تصفح حسب المؤلف "Sotgia, Salvatore"
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Cellular immune activation in Sardinian middle-aged, older adults and centenarians
Sotgia, Salvatore; Zinellu, Angelo; Mangoni, Arduino A; Serra, Roberta; Pintus, Gianfranco; Caruso, Calogero; Deiana, Luca; Carru, Ciriaco... more authors ... less authors ( Elsevier , 2017 , Article)In addition to viral infections, malignant disorders, autoimmune diseases, and allograft rejection episodes, neopterin increases in older people where it is found to be predictive of overall mortality. Thus, the serum ... -
Evaluation of Global Genomic DNA Methylation in Human Whole Blood by Capillary Electrophoresis UV Detection
Zinellu, Angelo; Sotgiu, Elisabetta; Assaretti, Stefano; Sotgia, Salvatore; Paliogiannis, Panagiotis; Pintus, Gianfranco; Mangoni, Arduino A.; Carru, Ciriaco... more authors ... less authors ( Hindawi Publishing Corporation , 2017 , Article)Alterations in global DNA methylation are implicated in various pathophysiological processes. The development of simple and quick, yet robust, methods to assess DNA methylation is required to facilitate its measurement and ... -
Identification of the Main Intermediate Precursor of l-Ergothioneine Biosynthesis in Human Biological Specimens
Sotgia, Salvatore; Mangoni, Arduino A.; Forteschi, Mauro; Murphy, Rhys B.; Elliot, David; Sotgiu, Elisabetta; Pintus, Gianfranco; Carru, Ciriaco; Zinellu, Angelo... more authors ... less authors ( MDPI AG , 2016 , Article)A capillary electrophoresis coupled to tandem mass spectrometry (CE–MS/MS) has been used to make a qualitative determination of hercynine—the main precursor of l-ergothioneine biosynthesis—in some key human biological ... -
Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells
Posadino, Anna Maria; Phu, Hoa Thi; Cossu, Annalisa; Giordo, Roberta; Fois, Marco; Thuan, Duong Thi Bich; Piga, Antonio; Sotgia, Salvatore; Zinellu, Angelo; Carru, Ciriaco; Pintus, Gianfranco... more authors ... less authors ( Elsevier , 2017 , Article)Green tea consumption has been shown to possess cancer chemopreventive activity. Polyphenol E (PE) is a widely used standardized green tea extract formulation. This study was designed to investigate the impact of PE on ... -
Strategies to enhance graphic and results interpretation of a regression-based approach for method comparison studies.
Sotgia, Salvatore; Mangoni, Arduino A; Pintus, Gianfranco; Carru, Ciriaco; Zinellu, Angelo ( Future Science Ltd , 2017 , Article)To improve the effectiveness of a previous regression-based approach for the assessment of the agreement between different analytical methods, two modifications/integrations to the original scheme by means of log10 ...