Browsing by Author "Brandão, Lucas"
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Biological Pathways Associated With the Development of Pulmonary Toxicities in Mesothelioma Patients Treated With Radical Hemithoracic Radiation Therapy: A Preliminary Study.
Crovella, Sergio; Revelant, Alberto; Muraro, Elena; Moura, Ronald Rodrigues; Brandão, Lucas; Trovò, Marco; Steffan, Agostino; Zacchi, Paola; Zabucchi, Giuliano; Minatel, Emilio; Borelli, Violetta... more authors ... less authors ( Frontiers Media , 2021 , Article)Radical hemithoracic radiotherapy (RHR), after lung-sparing surgery, has recently become a concrete therapeutic option for malignant pleural mesothelioma (MPM), an asbestos-related, highly aggressive tumor with increasing ... -
Different molecular pathways are disrupted in Pyoderma gangrenosum patients and are associated with the severity of the disease.
Moura, Ronald Rodrigues; Brandão, Lucas; Moltrasio, Chiara; Agrelli, Almerinda; Tricarico, Paola Maura; Maronese, Carlo Alberto; Crovella, Sergio; Marzano, Angelo Valerio... more authors ... less authors ( Nature Research , 2023 , Article)Pyoderma gangrenosum (PG) is a rare inflammatory skin disease classified within the spectrum of neutrophilic dermatoses. The pathophysiology of PG is yet incompletely understood but a prominent role of genetics facilitating ... -
Pleiotropic role of notch signaling in human skin diseases
Gratton, Rossella; Tricarico, Paola Maura; Moltrasio, Chiara; de Oliveira, Ana Sofia Lima Estevão; Brandão, Lucas; Marzano, Angelo Valerio; Zupin, Luisa; Crovella, Sergio... more authors ... less authors ( MDPI , 2020 , Article Review)Notch signaling orchestrates the regulation of cell proliferation, differentiation, migration and apoptosis of epidermal cells by strictly interacting with other cellular pathways. Any disruption of Notch signaling, either ... -
Variant Enrichment Analysis to Explore Pathways Disruption in a Necropsy Series of Asbestos-Exposed Shipyard Workers
Crovella, Sergio; Moura, Ronald Rodrigues; Brandão, Lucas; Vita, Francesca; Schneider, Manuela; Zanconati, Fabrizio; Finotto, Luigi; Zacchi, Paola; Zabucchi, Giuliano; Borelli, Violetta... more authors ... less authors ( MDPI , 2022 , Article)The variant enrichment analysis (VEA), a recently developed bioinformatic workflow, has been shown to be a valuable tool for whole-exome sequencing data analysis, allowing finding differences between the number of genetic ... -
Whole-Exome Sequencing in 10 Unrelated Patients with Syndromic Hidradenitis Suppurativa: A Preliminary Step for a Genotype-Phenotype Correlation.
Marzano, Angelo Valerio; Genovese, Giovanni; Moltrasio, Chiara; Tricarico, Paola Maura; Gratton, Rossella; Piaserico, Stefano; Garcovich, Simone; Boniotto, Michele; Brandão, Lucas; Moura, Ronald; Crovella, Sergio... more authors ... less authors ( Karger Publishers , 2022 , Article)The genetics of syndromic hidradenitis suppurativa (HS), an immune-mediated condition associated with systemic comorbidities such as inflammatory bowel diseases and arthritis, has not been completely elucidated. To describe ...