Browsing by Author "Caceci, Thomas"
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Common and Rare Genetic Variants Associated With Alzheimer's Disease
Marei, Hany E.; Althani, Asmaa; Suhonen, Jaana; El Zowalaty, Mohamed E.; Albanna, Mohammad A.; Cenciarelli, Carlo; Wang, Tengfei; Caceci, Thomas... more authors ... less authors ( WILEY PERIODICALS, INC. , 2016 , Article)Alzheimer's disease (AD) is one of the most devastating disorders. Despite the continuing increase of its incidence among aging populations, no effective cure has been developed mainly due to difficulties in early diagnosis ... -
Glioma extracellular vesicles for precision medicine: prognostic and theragnostic application
Marei, Hany E.; Althani, Asmaa; Afifi, Nahla; Hasan, Anwarul; Caceci, Thomas; Cifola, Ingrid; Caratelli, Sara; Sconocchia, Giuseppe; D’Agnano, Igea; Cenciarelli, Carlo... more authors ... less authors ( Springer , 2022 , Article Review)EV produced by tumour cells carry a diverse population of proteins, lipids, DNA, and RNA molecules throughout the body and appear to play an important role in the overall development of the disease state, according to ... -
Pandemic COVID-19 caused by SARS-CoV-2: genetic structure, vaccination, and therapeutic approaches
Marei, Hany E.; Althani, Asmaa; Afifi, Nahla; Pozzoli, Giacomo; Caceci, Thomas; Angelini, Franco; Cenciarelli, Carlo... more authors ... less authors ( Springer , 2021 , Article Review)We give a summary of SARS-genetic CoV-2’s structure and evolution, as well as current attempts to develop efficient vaccine and treatment methods for SARS-CoV-2 infection, in this article. Most therapeutic strategies are ... -
Recent perspective on CAR and Fcγ-CR T cell immunotherapy for cancers: Preclinical evidence versus clinical outcomes.
Marei, Hany E; Althani, Asma; Caceci, Thomas; Arriga, Roberto; Sconocchia, Tommaso; Ottaviani, Alessio; Lanzilli, Giulia; Roselli, Mario; Caratelli, Sara; Cenciarelli, Carlo; Sconocchia, Giuseppe... more authors ... less authors ( Elsevier , 2019 , Article)The chimeric antigen receptor Tcell (CAR-T cell) immunotherapy currently represents a hot research trend and it is expected to revolutionize the field of cancer therapy. Promising outcomes have been achieved using CAR-T ... -
Xeno-free trans-differentiation of adipose tissue-derived mesenchymal stem cells into glial and neuronal cells.
Elgamal, Aya; Althani A, Asmaa; Abd-Elmaksoud, Ahmed; Kassab, Mohammed; Farag, Amany; Lashen, Samah; Gabr, Mahmoud M; Zakaria, Mahmoud M; Alissawi, Mohga M; Ismail, Hossam El-Din Ali; Abd El Galil, Ahmed; Caceci, Thomas; Cenciarelli C, Carlo; Marei, Hany E... more authors ... less authors ( e-Century Publishing , 2019 , Article)Mesenchymal stem cells (MSCs) are undifferentiated cells that have the ability of self-renewal and trans-differentiation into other cell types. They hold out hope for finding a cure for many diseases. Nevertheless, there ...