Browsing by Author "Maayah, Zaid H."
Now showing items 1-4 of 4
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6-Formylindolo(3,2-b)carbazole Dampens Inflammation and Reduces Endotoxin-Induced Kidney Injury via Nrf2 Activation
Dhulkifle, Hevna; Sayed, Tahseen S.; Abunada, Hanan H.; Abulola, Sara M.; Alhoshani, Ali; Korashy, Hesham M.; Maayah, Zaid H.... more authors ... less authors ( American Chemical Society (ACS) , 2023 , Article)Patients with sepsis are at a high risk of morbidity and mortality due to multiple organ injuries caused by pathological inflammation. Although sepsis is accompanied by multiple organ injuries, acute renal injury is a ... -
Assessment of Native Myocardial T1 Mapping for Early Detection of Anthracycline-Induced Cardiotoxicity in Patients with Cancer: a Systematic Review and Meta-analysis
Mohamed, Amira A.; Elmancy, Layla Y.; Abulola, Sara M.; Al-Qattan, Sara A.; Mohamed Ibrahim, Mohamed Izham; Maayah, Zaid H.... more authors ... less authors ( Springer Nature , 2024 , Article)Anthracycline antibiotic is one of the most effective anti-tumor drugs used to manage certain types of breast cancers, lymphomas, and leukemias. However, anthracyclines induce a dose-dependent cardiotoxicity that may ... -
Endothelin Receptor Blocker Reverses Breast Cancer–Induced Cardiac Remodeling
Maayah, Zaid H.; Ferdaoussi, Mourad; Boukouris, Aristeidis E.; Takahara, Shingo; Das, Subhash K.; Khairy, Mostafa; Mackey, John R.; Pituskin, Edith; Sutendra, Gopinath; Paterson, D. Ian; Dyck, Jason R.B.... more authors ... less authors ( Elsevier , 2023 , Article)Background: Although some cancer therapies have overt and/or subclinical cardiotoxic effects that increase subsequent cardiovascular risk in breast cancer patients, we have recently shown that the breast tumor itself can ... -
Inhibition of cytochrome P450 epoxygenase promotes endothelium-to-mesenchymal transition and exacerbates doxorubicin-induced cardiovascular toxicity
Dhulkifle, Hevna; Therachiyil, Lubna; Hasan, Maram H.; Sayed, Tahseen S.; Younis, Shahd M.; Korashy, Hesham M.; Yalcin, Huseyin C.; Maayah, Zaid H.... more authors ... less authors ( Springer Nature , 2024 , Article)Background: Doxorubicin (DOX) is a potent chemotherapy widely used in treating various neoplastic diseases. However, the clinical use of DOX is limited due to its potential toxic effect on the cardiovascular system. Thus, ...