تصفح حسب المؤلف "Zhao J."
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A novel human pain insensitivity disorder caused by a point mutation in ZFHX2
Habib A.M.; Matsuyama A.; Okorokov A.L.; Santana-Varela S.; Bras J.T.; Aloisi A.M.; Emery E.C.; Bogdanov Y.D.; Follenfant M.; Gossage S.J.; Gras M.; Humphrey J.; Kolesnikov A.; Le Cann K.; Li S.; Minett M.S.; Pereira V.; Ponsolles C.; Sikandar S.; Torres J.M.; Yamaoka K.; Zhao J.; Komine Y.; Yamamori T.; Maniatis N.; Panov K.I.; Houlden H.; Ramirez J.D.; Bennett D.L.H.; Marsili L.; Bachiocco V.; Wood J.N.; Cox J.J.... more authors ... less authors ( Oxford University Press , 2018 , Article)Chronic pain is a major global public health issue causing a severe impact on both the quality of life for sufferers and the wider economy. Despite the significant clinical burden, little progress has been made in terms ... -
Modulation of proteomic and inflammatory signals by Bradykinin in podocytes
Saoud R.; Jaffa M.A.; Habib A.; Zhao J.; Al Hariri M.; Zhu R.; Hasan, Anwarul; Ziyadeh F.N.; Kobeissy F.; Mechref Y.; Jaffa A.A.... more authors ... less authors ( Elsevier B.V. , 2020 , Article)Podocyte damage is one of the hallmarks of diabetic nephropathy leading to proteinuria and kidney damage. The underlying mechanisms of podocyte injury are not well defined. Bradykinin (BK) was shown to contribute to diabetic ... -
Structure, nanomechanics, and dynamics of dispersed surfactant-free clay nanocomposite films
Zhang X.; Zhao J.; Snyder C.R.; Al-Enizi A.; Eltazahry A.; Simmons D.S.; Karim A.... more authors ... less authors ( John Wiley and Sons Inc. , 2018 , Article)The current work presents a new approach to achieve high quality dispersion of surfactant-free nanoclay tactoid particles in sub-micron thin films despite the absence of organic modifier. Natural Montmorillonite particles, ... -
Vascular cells proteome associated with bradykinin and leptin inflammation and oxidative stress signals
Hariri M.A.; Jaffa M.A.; Saoud R.; Zhao J.; Zhu R.; Jaffa A.A.; El-Achkar G.A.; Moussa M.; Kobeissy F.; Hassan A.; Ziyadeh F.N.; Mechref Y.; Jaffa A.A.... more authors ... less authors ( MDPI , 2020 , Article)Among the primary contributors to cardiovascular diseases are inflammation and oxidative imbalance within the vessel walls as well as the fibrosis of rat aortic smooth muscle cell (RASMC). Bradykinin (BK) and leptin are ...