• Gene Expression Profiling of Embryonic Human Neural Stem Cells and Dopaminergic Neurons from Adult Human Substantia Nigra 

      Marei, Hany E.; Althani, Asma; Afifi, Nahla; Michetti, Fabrizio; Pescatori, Mario; ... more authors ( Public Library of Science , 2011 , Article)
      Neural stem cells (NSC) with self-renewal and multipotent properties serve as an ideal cell source for transplantation to treat neurodegenerative insults such as Parkinson’s disease. We used Agilent’s and Illumina Whole ...
    • Human Olfactory Bulb Neural Stem Cells Expressing hNGF Restore Cognitive Deficit in Alzheimer's Disease Rat Model 

      Marei, Hany E.; Farag, Amany; Al-Thani, Asma; Afifi, Nahla; Abd-Elmaksoud, Ahmed; ... more authors ( Wiley , 2015 , Article)
      In this study, we aim to demonstrate the fate of allogenic adult human olfactory bulb neural stem/progenitor cells (OBNSC/NPCs) transplanted into the rat hippocampus treated with ibotenic acid (IBO), a neurotoxicant ...
    • Over-Expression of hNGF in Adult Human Olfactory Bulb Neural Stem Cells Promotes Cell Growth and Oligodendrocytic Differentiation 

      Marei, Hany E.; Althani, Asmaa; Afifi, Nahla; Abd-Elmaksoud, Ahmed; Bernardini, Camilla; ... more authors ( Public Library of Science ONE Staff , 2013 , Article)
      The adult human olfactory bulb neural stem/progenitor cells (OBNC/PC) are promising candidate for cell-based therapy for traumatic and neurodegenerative insults. Exogenous application of NGF was suggested as a promising ...
    • The Qatar Biobank: background and methods 

      Al Kuwari, Hanan; Al-Thani, Asma; Al Marri, Ajayeb; Al Kaabi, Abdulla; Abderrahim, Hadi; ... more authors ( BioMed Central , 2015 , Article)
      Background: The Qatar Biobank aims to collect extensive lifestyle, clinical, and biological information from up to 60,000 men and women Qatari nationals and long-term residents (individuals living in the country for ≥15 ...
    • Thousands of Qatari genomes inform human migration history and improve imputation of Arab haplotypes 

      Razali, Rozaimi Mohamad; Rodriguez-Flores, Juan; Ghorbani, Mohammadmersad; Naeem, Haroon; Aamer, Waleed; ... more authors ( Nature Research , 2021 , Article)
      Arab populations are largely understudied, notably their genetic structure and history. Here we present an in-depth analysis of 6,218 whole genomes from Qatar, revealing extensive diversity as well as genetic ancestries ...
    • Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits 

      Thareja, Gaurav; Al-Sarraj, Yasser; Belkadi, Aziz; Almotawa, Maryam; Ismail, Said; ... more authors ( Springer Nature , 2021 , Article)
      Clinical laboratory tests play a pivotal role in medical decision making, but little is known about their genetic variability between populations. We report a genome-wide association study with 45 clinically relevant traits ...
    • Willingness to participate in genome testing: a survey of public attitudes from Qatar 

      Abdul-Rahim, Hanan; Ismail, Said; Hasan, Amel; Fadl, Tasnim; Khaled, Salma; ... more authors ( Springer , 2020 , Article)
      Genomics has the potential to revolutionize medical approaches to disease prevention, diagnosis, and treatment, but it does not come without challenges. The success of a national population-based genome program, like the ...