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    Browsing by Author "Kamareddine, Layla"

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        ASSESSING THE CURRENT STANDING OF HAMAD MEDICAL CORPORATION BLOOD DONOR CENTER IN QATAR AND DEVELOPING A FORECAST MODEL FOR THE BLOOD STOCK NEEDS DURING THE 2022 WORLD CUP EVENT 

        QUSH, ABEER SULEIMAN (2019 , Master Thesis)
        Background: In four years from now, Qatar will host the 2022 World Cup competition which requires high level of preparedness and readiness in different sectors including health care. Among different sub-sections of health, ...
      • Diet-induced mechanical stress promotes immune and metabolic alterations in the Drosophila melanogaster digestive tract 

        Abeer, Qush; Yassine, Hadi M.; Zeidan, Asad; Kamareddine, Layla ( Elsevier , 2025 , Article)
        A fundamental query in immunology is how cells recognize danger in the tissue milieu. For many years, standpoints were mainly centered around damaged cells or structures of invading pathogens, like lipopolysaccharide, being ...
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        Drosophila as a Model Organism in Host–Pathogen Interaction Studies 

        Younes, Salma; Al-Sulaiti, Asma; Abdulwahab Ahmed Nasser, Elham; Najjar, Hoda; Kamareddine, Layla ( Frontiers Media , 2020 , Article Review)
        Owing to the genetic similarities and conserved pathways between a fruit fly and mammals, the use of the Drosophila model as a platform to unveil novel mechanisms of infection and disease progression has been justified and ...
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        Editorial: Unconventional animal models in infectious disease research, volume II 

        Younes, Salma; Zein, Nouran; Abunasser, Shaden; Kamareddine, Layla; Kirienko, Natalia V.; Nasrallah, Gheyath K.... more authors ... less authors ( Frontiers Media , 2023 , Article)
        Infectious diseases remain a serious health threat globally, an actuality that necessitates ongoing research in this field. Among different research modalities, the use of animal models to unravel host-pathogen interactions ...
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        The effect of novel nitrogen-based chalcone analogs on colorectal cancer cells: Insight into the molecular pathways 

        Arij Fouzat, Hassan; Hussein, Ola; Al-Barazenji, Tara; Allouch, Asma; Kamareddine, Layla; Malki, Ahmed; Moustafa, Ala‐Eddin Al; Khalil, Ashraf... more authors ... less authors ( Elsevier , 2024 , Article)
        In colorectal cancer (CRC), aberrations in KRAS are associated with aggressive tumorigenesis and an overall low survival rate because of chemoresistance and adverse effects. Ergo, complementary, and integrative medicines ...
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        Enteric pathogens modulate metabolic homeostasis in the Drosophila melanogaster host 

        Hoda, Najjar; Al-Ashmar, Sarah; Qush, Abeer; Al-Asmar, Jawaher; Rashwan, Sara; Elgamal, Abdelrahman; Zeidan, Asad; Kamareddine, Layla... more authors ... less authors ( Elsevier , 2022 , Article)
        On quotidian basis, living beings work out an armistice with their microbial flora and a scuffle with invading pathogens to maintain a normal state of health. Although producing virulence factors and escaping the host's ...
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        The Impact of Environmental and Anthropogenic Factors on the Transmission Dynamics of Vector Borne Diseases 

        Kamareddine, Layla ( Elsevier , 2019 , Article)
        Vector-borne diseases have been widely associated with human morbidity and mortality. The predominance of vector-borne diseases is not exclusive to particular areas, as such diseases are dispersed across the globe. Generally, ...
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        Intake of Caffeine Containing Sugar Diet Remodels Gut Microbiota and Perturbs Drosophila melanogaster Immunity and Lifespan 

        Abeer, Qush; Al Khatib, Hebah A.; Rachid, Hajar; Al-Tamimi, Hend; Al-Eshaq, Alyaa; Al-adwi, Shaima; Yassine, Hadi M.; Kamareddine, Layla... more authors ... less authors ( Elsevier , 2023 , Article)
        The diet-microbiome-immunity axis is one among the many arms that draw up the “we are what we intake” proclamation. As such, studies on the effect of food and beverage intake on the gut environment and microbiome and on ...
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        The Microbiota and Gut-Related Disorders: Insights from Animal Models 

        Kamareddine, Layla; Najjar, Hoda; Abdulkader, Hadil; Al-Asmakh, Maha; Sohail, Muhammad Umar ( MDPI , 2020 , Article Review)
        Over the past decade, the scientific committee has called for broadening our horizons in understanding host–microbe interactions and infectious disease progression. Owing to the fact that the human gut harbors trillions ...
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        The mosquito melanization response requires hierarchical activation of non-catalytic clip domain serine protease homologs. 

        El Moussawi, Layla; Nakhleh, Johnny; Kamareddine, Layla; Osta, Mike ( Public Library of Science , 2019 , Article)
        Serine protease cascades regulate important insect immune responses namely melanization and Toll pathway activation. An important component of these cascades are clip-domain serine protease homologs (cSPHs), which are ...
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        SARS-CoV-2 and immune-microbiome interactions: Lessons from respiratory viral infections 

        Farhan, Cyprian; Sohail, Muhammad Umar; Abdelhafez, Ibrahim; Salman, Salma; Attique, Zakria; Kamareddine, Layla; Al-Asmakh, Maha... more authors ... less authors ( Elsevier , 2021 , Article)
        By the beginning of 2020, infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had rapidly evolved into an emergent worldwide pandemic, an outbreak whose unprecedented consequences highlighted ...
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        Unraveling the proteomic signatures of coronary artery disease and hypercholesterolemia. 

        Anlar, Gulsen Guliz; Pedersen, Shona; Al Ashmar, Sarah; Krzyslak, Hubert; Kamareddine, Layla; Zeidan, Asad... more authors ... less authors ( The Association of Basic Medical Sciences , 2024 , Article)
        Atherosclerosis, a leading cause of coronary artery disease (CAD), is heavily influenced by hypercholesterolemia (HC). Proteomics research has shown promise in identifying biological markers for CAD diagnosis and prognosis. ...

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