Browsing by Author "El Sayed, Khalid"
Now showing items 1-2 of 2
-
Design, synthesis, and validation of novel nitrogen-based chalcone analogs against triple negative breast cancer
Elkhalifa, Dana; Siddique, Abu Bakar; Qusa, Mohammed; Cyprian, Farhan S.; El Sayed, Khalid; Alali, Feras; Al Moustafa, Ala-Eddin; Khalil, Ashraf... more authors ... less authors ( Elsevier Masson s.r.l. , 2020 , Article)Great strides have been made in triple negative breast cancer (TNBC) treatment, which represents 20% of total predicted annual US breast cancer (BC) cases. Despite the development of several therapeutics, TNBC patients ... -
Structure-activity relationship investigation of methoxy substitution on anticancer pyrimido[4,5-c]quinolin-1(2H)-ones
Metwally, Kamel; Khalil, Ashraf; Sallam, Asmaa; Pratsinis, Harris; Kletsas, Dimitris; El Sayed, Khalid... more authors ... less authors (2013 , Article)Pyrimido[4,5-c]quinolin-1(2H)-one derivatives were shown to exert interesting biological activities including anticancer, antimicrobial, and cardiovascular. Substitution with methoxy groups played a crucial role in the ...