تصفح حسب المؤلف "Kannan, Surya"
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Between Inflammation and Autophagy: The Role of Leptin-Adiponectin Axis in Cardiac Remodeling
Kamareddine, Layla; Ghantous, Crystal; Allouch, Soumaya; Al-Ashmar, Sara; Anlar, Gulsen; Kannan, Surya; Djouhri, Laiche; Korashy, Hesham; Agouni, Abdelali; Zeidan, Asad... more authors ... less authors ( Dove Medical Press , 2021 , Article Review)Cardiac remodeling is the process by which the heart adapts to stressful stimuli, such as hypertension and ischemia/reperfusion; it ultimately leads to heart failure upon long- term exposure. Autophagy, a cellular catabolic ... -
The Exposure to Human Breast Cancer Cells Altered 14 Post-Translational Modifications of Human Serum Albumin.
Kannan, Surya; Souchelnytskyi, Serhiy ( International Federation of Clinical Chemistry and Laboratory Medicine , 2022 , Article)Serum albumin is in contact with practically all cells in the human body, including tumor cells in cancer patients. The purpose of this study was to explore whether cancer cells affect post-translational modifications ... -
Glycosylation is a novel TGF?1-independent post-translational modification of Smad2
Gotoh, Takaya; Iwahana, Hiroyuki; Kannan, Surya; Marei, Reham Ghazal; Mousa, Hanaa; Elgamal, Mahmoud; Souchelnytskyi, Serhiy... more authors ... less authors ( Elsevier B.V. , 2019 , Article)Smad2 is a crucial component of intracellular signaling by transforming growth factor-? (TGF?). Here we describe that Smad2 is glycosylated, which is a novel for Smad2 post-translational modification. We showed that the ... -
Novel Post-translational Modifications in Human Serum Albumin
Kannan, Surya; Krishnankutty, Roopesh; Souchelnytskyi, Serhiy ( Bentham , 2022 , Article)Aim: This study aims to identify novel post-translational modifications in human serum albumin by mass spectrometry. Background: Serum albumin is the most abundant protein in plasma, has many physiological functions, and ... -
Post-translational modifications of albumin in cancer a rich source for diagnostic and monitoring of treatment
Kannan, Surya; Souchelnytski, Serhiy ( Qatar University Press , 2020 , Poster)Albumin is in contact with all cells in a body. This major protein in a plasma accesses all tissues and organs and has a number of different roles. Albumin was found to have more than 50 post-translational modifications ... -
Review of Post-translational Modification of Human Serum Albumin
Kannan, Surya; Souchelnytskyi, Serhiy ( Bentham , 2022 , Article)Post-translational modifications (PTMs) may affect the functions of human serum albumin. Here we review reports of novel PTMs of human serum albumin. This study reviewed one hundred twenty-three recently reported novel ...