Browsing by Author "Toft, Egon"
Now showing items 1-12 of 12
-
A Qualitative Study on Implementation of the Intelligent Bed: Findings from a Rehabilitation Ward at a Large Chinese Tertiary Hospital
Cai, Hao; Krebs, Hans Jorgen; Tao, Yingshan; Hansen, John; Hansen, Ruihuan; Cai, Yanguang; Toft, Egon; Dinesen, Birthe... more authors ... less authors ( Springer New York LLC , 2016 , Article)The intelligent bed, a mechanical hospital bed equipped with several electronic sensor functions, is an assistive healthcare solution intended to reduce the manual workload of health professionals by providing valuable ... -
Arrhythmogenic calmodulin E105A mutation alters cardiac RyR2 regulation leading to cardiac dysfunction in zebrafish
Da'as, Sahar I; Thanassoulas, Angelos; Calver, Brian L; Beck, Konrad; Salem, Rola; Saleh, Alaaeldin; Kontogianni, Iris; Al-Maraghi, Ali; Nasrallah, Gheyath K; Safieh-Garabedian, Bared; Toft, Egon; Nounesis, George; Lai, F Anthony; Nomikos, Michail... more authors ... less authors ( Wiley , 2019 , Article)Calmodulin (CaM) is a universal calcium (Ca )-binding messenger that regulates many vital cellular events. In cardiac muscle, CaM associates with ryanodine receptor 2 (RyR2) and regulates excitation-contraction coupling. ... -
The Arrhythmogenic E105A CAM Mutation Dysregulates Normal Cardiac Function in Zebrafish by Altering CAM-Ca2+ and CAM-RyR2 Interactions
Nomikos, Michail; I. Da’as, Sahar; Thanassoulas, Angelos; Salem, Rola; L. Calver, Brian; Saleh, Alaaeldin; Al-Maraghi, Ali; K. Nasrallah, Gheyath; Safieh-Garabedian, Bared; Toft, Egon; Nounesis, George; Lai, F. Anthony... more authors ... less authors ( Elsevier , 2019 , Article)Calmodulin (CaM) is a multifunctional calcium (Ca2+)-binding messenger that directly interacts with the cardiac ryanodine receptor 2 (RyR2), a large transmembrane Ca2+ channel that mediates Ca2+ release from the sarcoplasmic ... -
Defective Interaction of Cam with RyR2 Cam-Binding Pocket Might Contribute to Arrhythmogenic Cardiac Disease
Nomikos, Michail; Thanassoulas, Angelos; Vassilakopoulou, Vyronia; L. Calver, Brian; Livaniou, Evangelia; Safieh-Garabedian, Bared; Toft, Egon; Nounesis, George; Lai, F. Anthony... more authors ... less authors ( Elsevier , 2020 , Article)Ryanodine receptor 2 (RyR2) is a large transmembrane calcium (Ca2+) release channel that mediates Ca2 release from the sarcoplasmic reticulum to activate cardiac muscle contraction. Calmodulin (CaM) regulation of RyR2 is ... -
Diagnosing coronary artery disease by sound analysis from coronary stenosis induced turbulent blood flow: diagnostic performance in patients with stable angina pectoris
Winther, Simon; Schmidt, Samuel Emil; Holm, Niels Ramsing; Toft, Egon; Struijk, Johannes Jan; Bøtker, Hans Erik; Bøttcher, Morten... more authors ... less authors ( Springer Netherlands / Society for Cardiovascular Imaging , 2016 , Article)Optimizing risk assessment may reduce use of advanced diagnostic testing in patients with symptoms suggestive of stable coronary artery disease (CAD). Detection of diastolic murmurs from post-stenotic coronary turbulence ... -
Metformin in pregnancy to avert gestational diabetes in women at high risk: Meta-analysis of randomized controlled trials.
Doi, Suhail A R; Furuya-Kanamori, Luis; Toft, Egon; Musa, Omran A H; Islam, Nazmul; Clark, Justin; Thalib, Lukman... more authors ... less authors ( Wiley , 2019 , Article Review)Previous randomized and observational studies on the efficacy of metformin in pregnancy to reduce incident gestational diabetes mellitus (GDM) in women at high risk (obesity, polycystic ovary syndrome [PCOS], or pregestational ... -
Metformin is comparable to insulin for pharmacotherapy in gestational diabetes mellitus: A network meta-analysis evaluating 6046 women.
Musa, Omran A H; Syed, Asma; Mohamed, Aisha M; Chivese, Tawanda; Clark, Justin; Furuya-Kanamori, Luis; Xu, Chang; Toft, Egon; Bashir, Mohammed; Abou-Samra, Abdul Badi; Thalib, Lukman; Doi, Suhail A... more authors ... less authors ( Elsevier , 2021 , Article)The comparative efficacy of gestational diabetes (GDM) treatments lack conclusive evidence for choice of first-line treatment. The aim of this study was to compare the efficacy of metformin and glibenclamide to insulin ... -
Personalized telehealth in the future: A global research agenda
Dinesen, Birthe; Nonnecke, Brandie; Lindeman, David; Toft, Egon; Kidholm, Kristian; Jethwani, Kamal; Young, Heather M; Spindler, Helle; Oestergaard, Claus Ugilt; Southard, Jeffrey A; Gutierrez, Mario; Anderson, Nick; Albert, Nancy M; Han, Jay J; Nesbitt, Thomas... more authors ... less authors ( JMIR Publications Inc. , 2016 , Article Review)As telehealth plays an even greater role in global health care delivery, it will be increasingly important to develop a strong evidence base of successful, innovative telehealth solutions that can lead to scalable and ... -
Physical activity in pregnancy prevents gestational diabetes: A meta-analysis
Suhail A.R., Doi; Furuya-Kanamori, Luis; Toft, Egon; Musa, Omran A.H.; Mohamed, Aisha M.; Clark, Justin; Thalib, Lukman... more authors ... less authors ( Elsevier , 2020 , Article)AimsThe effectiveness of physical activity (PA) programs for prevention of gestational diabetes (GDM) lacks conclusive evidence. The aim of this study was to generate clear evidence regarding the effectiveness of physical ... -
Randomized clinical trial comparing abluminal biodegradable polymer sirolimus-eluting stents with durable polymer sirolimus-eluting stents: Nine months angiographic and 5-year clinical outcomes
Zhang, Haijun; Wang, Xiangfei; Deng, Wei; Wang, Shenguo; Ge, Junbo; Toft, Egon... more authors ... less authors ( Wolters Kluwer Health, Inc , 2016 , Article)Background: The biodegradable polymer drug-eluting stents (DES) were developed to improve vascular healing. However, further data and longer-term follow-up are needed to confirm safety and efficacy of these stents. This ... -
Solely abluminal drug release from coronary stents could possibly improve reendothelialization
Zhang, Haijun; Deng, Wei; Wang, Xiangfei; Wang, Shenguo; Ge, Junbo; Toft, Egon... more authors ... less authors ( John Wiley and Sons Inc. , 2016 , Article)Objectives To compare a new stent with an asymmetric coating, eluting the drug to the abluminal surface, to a stent with a conventional coating eluting the drug both to the luminal and the abluminal side. Background Stents ... -
This House believes that considering the continuous quarantine and precautionary measures should be of a priority over lifting the restrictions to avoid the negative economic and social consequences
Baraka, Jawaher Z A; Toft, Egon; El-Awaisi, Alla; Abdul Rahim, Hanan; Alali, Feras; Doi, Suhail; Salim, Bana; Saeed, Aysha; Rana, Shahryar; Nazar, Fatima; Malik, Shaza; Daniyal, Ahmed... more authors ... less authors ( College of Medicine - Qatar University , 2020 , Video)NA