Browsing by Author "Abdel-latif, Rania"

Now showing items 1-3 of 3

    • A population study of clinically actionable genetic variation affecting drug response from the Middle East 

      Jithesh, Puthen Veettil; Abuhaliqa, Mohammed; Syed, Najeeb; Ahmed, Ikhlak; El Anbari, Mohammed; ... more authors ( Nature Research , 2022 , Article)
      Clinical implementation of pharmacogenomics will help in personalizing drug prescriptions and alleviate the personal and financial burden due to inefficacy and adverse reactions to drugs. However, such implementation is ...

    • Dihydropyrimidine Dehydrogenase Deficiency (DPYD) Genotyping-Guided Fluoropyrimidine-Based Adjuvant Chemotherapy for Breast Cancer. A Cost-Effectiveness Analysis 

      Abushanab, Dina; Mohamed, Shaban; Abdel-latif, Rania; Moustafa, Diala Alhaj; Marridi, Wafa; ... more authors ( Springer Nature , 2025 , Article)
      Background and Objective: While standard doses of adjuvant fluoropyrimidine-based chemotherapies are generally safe for most patients, the risk of severe adverse drug reactions (ADRs) is increased for those with dihydropyrimidine ...

    • QPGx-CARES: Qatar pharmacogenetics clinical applications and research enhancement strategies 

      Abdel-latif, Rania; Badji, Radja; Mohammed, Shaban; Al-Muftah, Wadha; Mbarek, Hamdi; ... more authors ( John Wiley and Sons Inc , 2024 , Article Review)
      Pharmacogenetic (PGx)-informed medication prescription is a cutting-edge genomic application in contemporary medicine, offering the potential to overcome the conventional "trial-and-error" approach in drug prescription. ...