Browsing by Author "Smith, Trevor"

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Activation of K7 channels with the anticonvulsant retigabine alleviates neuropathic pain behaviour in the streptozotocin rat model of diabetic neuropathy.

Djouhri, Laiche; Malki, MohammedImad; Zeidan, Asad; Nagi, Karim; Smith, Trevor ( Taylor & Francis (Routledge) , 2019 , Article)
Diabetic peripheral neuropathy (DPN) is the most incapacitating complication of diabetes mellitus. Up to 50% of patients with DPN develop peripheral neuropathic pain (PNP). The underlying ionic and molecular mechanisms of ...
Cutaneous Aβ-Non-nociceptive, but Not C-Nociceptive, Dorsal Root Ganglion Neurons Exhibit Spontaneous Activity in the Streptozotocin Rat Model of Painful Diabetic Neuropathy .

Djouhri, Laiche; Zeidan, Asad; Abd El-Aleem, Seham A; Smith, Trevor ( Frontiers Media , 2020 , Article)
Diabetic peripheral neuropathic pain (DPNP) is the most devastating complication of diabetes mellitus. Unfortunately, successful therapy for DPNP remains a challenge because its pathogenesis is still elusive. However, DPNP ...