Pyrrolizidine alkaloids from alkanna orientalis (L.) Boiss

Abstract

Three pyrrolizidine alkaloids; 7-angelyl retronecine (I), 9-angelyl retronescine (II), and dihydroxytriangularine (III) were isolated by DCCC and VLC from Alkanna orientalis growing in Egypt. Their structures were elucidated by MS, 'H NMR and "C NMR spectral analyses. (II) (9-angelyl retronecine), was isolated for the first time from the genus Alkanna. In addition, three other minor alkaloids have also been detected by TLC.