عرض بسيط للتسجيلة

المؤلفAlbinali, Kholoud E.
المؤلفZagho, Moustafa M.
المؤلفDeng, Yonghui
المؤلفElzatahry, Ahmed A.
تاريخ الإتاحة2020-06-23T20:45:39Z
تاريخ النشر2019
اسم المنشورInternational Journal of Nanomedicine
المصدرScopus
الرقم المعياري الدولي للكتاب11769114
معرّف المصادر الموحدhttp://dx.doi.org/10.2147/IJN.S193981
معرّف المصادر الموحدhttp://hdl.handle.net/10576/15092
الملخصMagnetic core–shell nanocarriers have been attracting growing interest owing to their physicochemical and structural properties. The main principles of magnetic nanoparticles (MNPs) are localized treatment and stability under the effect of external magnetic fields. Furthermore, these MNPs can be coated or functionalized to gain a responsive property to a specific trigger, such as pH, heat, or even enzymes. Current investigations have been focused on the employment of this concept in cancer therapies. The evaluation of magnetic core–shell materials includes their magnetization properties, toxicity, and efficacy in drug uptake and release. This review discusses some categories of magnetic core–shell drug carriers based on Fe2O3 and Fe3O4 as the core, and different shells such as poly(lactic-co-glycolic acid), poly(vinylpyrrolidone), chitosan, silica, calcium silicate, metal, and lipids. In addition, the review addresses their recent potential applications for cancer treatment.
راعي المشروعThe authors would like to acknowledge Qatar University for funding the project: GCC Co-Fund Program Grant #GCC-2017-001 and student grant QUST-1-CAS-2019-36. The publication of this article was funded by the Qatar National Library.
اللغةen
الناشرDove Medical Press Ltd.
الموضوعActive targeting
Controlled release
Core
Drug carriers
Magnetic
Mesoporous
Passive targeting
Shell
Targeted cancer treatment
العنوانA perspective on magnetic core–shell carriers for responsive and targeted drug delivery systems
النوعArticle Review
الصفحات1707-1723
رقم المجلد14
dc.accessType Open Access


الملفات في هذه التسجيلة

Thumbnail

هذه التسجيلة تظهر في المجموعات التالية

عرض بسيط للتسجيلة