Show simple item record

AuthorSundarabharathi, Lakshmanaperumal
AuthorChinnaswamy, Mahendran
AuthorPonnamma, Deepalekshmi
AuthorParangusan, Hemalatha
AuthorAl-Maadeed, Mariam Al Ali
Available date2020-06-23T20:45:41Z
Publication Date2019
Publication NameJournal of the American Ceramic Society
ResourceScopus
ISSN27820
URIhttp://dx.doi.org/10.1111/jace.15866
URIhttp://hdl.handle.net/10576/15127
AbstractDual doped calcium apatite has been widely focused as it enhances the osteoconductive property for the possible applications in orthopedic and dental implants. In this work, we investigate the antimicrobial and bioactive properties of cerium/strontium (Ce3+/Sr2+) co‐substituted hydroxyapatite (HA ) nanoparticles synthesized by sol‐gel assisted precipitation method. The structure, morphology, functional groups, photoluminescence, and thermal stability of the developed systems are examined. The comparative studies performed among the pure HA , Sr2+, and Ce3+‐substituted HA nanoparticles illustrate higher antibacterial activity with lowered apatite‐forming ability and biocompatibility for the Ce3+‐substituted HA . However, the Ce3+/Sr2+co‐substituted HA exhibits better biocompatibility, apatite‐forming ability, and good antimicrobial properties. Sr2+ ion inclusion leads to better biological properties and compromise the cytotoxic nature of the Ce3+‐HA . In addition, the Ce3+/Sr2+‐HA nanoparticles prevent thermal decomposition up to 700°C, pointing also toward the possibility of this co‐substituted HA in bone implant applications.
SponsorThis work has been funded by the University Grants Commission (UGC) SERO, Hyderabad, India (No. F MRF-6819/16) (SERO/UGC). The author Dr. C. Mahendran is grateful for the financial support.
Languageen
PublisherBlackwell Publishing Inc.
Subjectbioactivity
biocompatibility
hydroxyapatite
live cell imaging
Sol-gel
TitleInvestigation of antimicrobial properties and in-vitro bioactivity of Ce3+-Sr2+dual-substituted nano hydroxyapatites
TypeArticle
Pagination144-157
Issue Number1
Volume Number102
dc.accessType Abstract Only


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record