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المؤلفBouallagui, Zouhaier
المؤلفMahmoudi, Asma
المؤلفMaalej, Amina
المؤلفHadrich, Fatma
المؤلفIsoda, Hiroko
المؤلفSayadi, Sami
تاريخ الإتاحة2020-08-18T08:34:15Z
تاريخ النشر2019
اسم المنشورAnti-Cancer Agents in Medicinal Chemistry
المصدرScopus
الرقم المعياري الدولي للكتاب18715206
معرّف المصادر الموحدhttp://dx.doi.org/10.2174/1871520619666190416101622
معرّف المصادر الموحدhttp://hdl.handle.net/10576/15558
الملخصAims: This study was designed to investigate the phytochemical profile and the cytotoxic activities of the eco-friendly extracts of olive leaves from Chemlali cultivar. Materials and Methods: The Phenolic composition of olive leaves extracts, the antioxidant activity and the cytotoxic effects against MCF-7 and HepG2 cells were determined. Results: Olive leaves extracts showed relevant total polyphenols contents. Oleuropein was the major detected phenolic compound reaching a concentration of 16.9 mg/ml. The antioxidant potential of the studied extracts varied from 23.7 to 46.5mM Trolox equivalents as revealed by DPPH and ABTS assays. Cytotoxicity experiments showed similar trends for both HepG2 and MCF-7 cells with the infusion extract being the most active. Conclusion: This study denotes that olive leaves may have great potential as endless bioresource of valuable bioactive compounds which may have a wide application. - 2019 Bentham Science Publishers.
راعي المشروعThis work was supported by the Tunisian Ministery of Higher Education and Scientific Research under the contract program for Laboratory of Environmental Bioprocesses at Centre of Biotechnology of Sfax. This work was also partially supported by the JICA/JST Science and Technology Research Partnership for Sustainable Development (SATREPS) Project (A6A24087): �Valorization of Bio-resources in Semi-arid and Arid Land for Regional Development''.
اللغةen
الناشرBentham Science Publishers
الموضوعBioactivities
Leaves
Olea europaea
Phytochemical profile
Polyphenols
�Chemlali'' cultivar
العنوانContribution of major polyphenols to the antioxidant profile and cytotoxic activity of olive leaves
النوعArticle
الصفحات1651-1657
رقم العدد13
رقم المجلد19
dc.accessType Abstract Only


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