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المؤلفMahmoud, Abdelrahman
المؤلفNaser, Mohammed
المؤلفAbdelrasool, Mahmoud
المؤلفJama, Khalid
المؤلفHussein, Mohamed
المؤلفAbdulkareem, Asma
المؤلفKasak, Peter
المؤلفPopelka, Anton
تاريخ الإتاحة2020-10-22T07:00:24Z
تاريخ النشر2020
اسم المنشورQatar University Annual Research Forum & Exhibition 2020
الاقتباسMahmoud A., Naser M., Abdelrasool M., Jama K., Hussein M., Abdulkareem A., Kasak P., Popelka A., "Development of PLA Fibers as an Antimicrobial Agent with enhanced infection resistance using electrospinning/plasma technology", Qatar University Annual Research Forum and Exhibition (QUARFE 2020), Doha, 2020, https://doi.org/10.29117/quarfe.2020.0079
معرّف المصادر الموحدhttps://doi.org/10.29117/quarfe.2020.0079
معرّف المصادر الموحدhttp://hdl.handle.net/10576/16614
الملخصHumans are vulnerable and easily prone to all kind of injuries, diseases, and traumas that can be damaging to their tissues (including its building unit, cells), bones, or even organs. Therefore, they would need assistance in healing or re-growing once again. Medical scaffolds have emerged over the past decades as one of the most important concepts in the tissue engineering field as they enable and aide the re-growth of tissues and their successors. An optimal medical scaffold should be addressing the following factors: biocompatibility, biodegradability, mechanical properties, scaffold architecture/porosity, precise three-dimensional shape and manufacturing technology. There are several materials utilized in the fabrication of medical scaffolds, but one of the most extensively studied polymers is polylactic acid (PLA). PLA is biodegradable thermoplastic aliphatic polyester that is derived from naturally produced lactic acid. PLA is characterized with its excellent mechanical properties, biodegradability, promising eco-friendly, and excellent biocompatibility. PLA can be fabricated into nanofibers for medical scaffolds used through many techniques; electrospinning is one of the widely used methods for such fabrication. Electrospinning is a favorable technique because in the preparation of scaffolds, some parameters such as fiber dimensions, morphology, and porosity are easily controlled. A problem that is associated with medical scaffolds, such as inflammation and infection, was reported in many cases resulting in a degradation of tissues. Therefore, a surface modification was thought of as a needed solution which mostly focuses on an incorporation of extra functionalities responsible for the surface free energy increase (wettability). Therefore, plasma technique was a favorable solution for the surface treatment and modification. Plasma treatment enables the formation of free radicals. These radicals can be easily utilized for grafting process. Subsequently, ascorbic acid (ASA) could be incorporated as anti-inflammatory and anti-infection agent on the plasma pretreated surface of scaffolds.
اللغةen
الناشرQatar University Press
الموضوعPLA; Fibers; Antimicrobial agent
العنوانDevelopment of PLA Fibers as an Antimicrobial Agent with enhanced infection resistance using electrospinning/plasma technology
النوعPoster
dc.accessType Open Access


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