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AuthorSobolčiak, Patrik
AuthorPopelka, Anton
AuthorMičušík, Matej
AuthorSláviková, Monika
AuthorKrupa, Igor
AuthorMosnáček, Jaroslav
AuthorTkáč, Ján
AuthorLacík, Igor
AuthorKasák, Peter
Available date2020-12-02T07:03:52Z
Publication Date2017
Publication NameJournal of Colloid and Interface Science
ResourceScopus
ISSN219797
URIhttp://dx.doi.org/10.1016/j.jcis.2017.04.020
URIhttp://hdl.handle.net/10576/17171
AbstractSimple and robust methods for modifying hydrophobic polymer surfaces with zwitterionic polymers using UV irradiation were developed. Two random zwitterionic copolymers consisting of either carboxybetaine or sulfobetaine methacrylamide monomers and monomers bearing a photolabile azidophenyl group were directly photoimmobilized on polymeric surfaces (polyester, polyethylene and polystyrene) via covalent interactions in a spatially controlled manner. These copolymers were also electrospun to form self-standing mats. The modified surfaces were characterized by X-ray photoelectron spectroscopy, atomic force microscopy, infrared spectroscopy and contact angle measurements. The electrospinning method involved the use of a trifluoroethanol solution with a copolymer concentration in the range from 2 to 10 wt.%. BHK 21 cell adhesion to both modified surfaces and mats was dramatically reduced compared to unmodified surfaces.
Languageen
PublisherAcademic Press Inc.
SubjectCell adhesion
Electrospinning
Photoimmobilization
Poly(carboxybetaine)
Poly(sulfobetaine)
Zwitterionic polymers
TitlePhotoimmobilization of zwitterionic polymers on surfaces to reduce cell adhesion
TypeArticle
Pagination294-303
Volume Number500
dc.accessType Abstract Only


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