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المؤلفPal, Manas
المؤلفWan, Li
المؤلفZhu, Yongheng
المؤلفLiu, Yupu
المؤلفLiu, Yang
المؤلفGao, Wenjun
المؤلفLi, Yuhui
المؤلفZheng, Gengfeng
المؤلفElzatahry, Ahmed A.
المؤلفAlghamdi, Abdulaziz
المؤلفDeng, Yonghui
المؤلفZhao, Dongyuan
تاريخ الإتاحة2021-07-05T10:58:28Z
تاريخ النشر2016
اسم المنشورBiomaterials
المصدرScopus
معرّف المصادر الموحدhttp://dx.doi.org/10.1016/j.biomaterials.2016.07.001
معرّف المصادر الموحدhttp://hdl.handle.net/10576/21061
الملخصDue to the increased morbidity and mortality resulting from heart valve diseases, there is a growing demand for off-the-shelf implantable tissue engineered heart valves (TEHVs). Despite the significant progress in recent years in improving the design and performance of TEHV constructs, viable and functional human implantable TEHV constructs have remained elusive. The recent advances in micro and nanoscale technologies including the microfabrication, nano-microfiber based scaffolds preparation, 3D cell encapsulated hydrogels preparation, microfluidic, micro-bioreactors, nano-microscale biosensors as well as the computational methods and models for simulation of biological tissues have increased the potential for realizing viable, functional and implantable TEHV constructs. In this review, we aim to present an overview of the importance and recent advances in micro and nano-scale technologies for the development of TEHV constructs. 2016 Elsevier Ltd
راعي المشروعThe authors acknowledge the Natural Sciences and Engineering Research of Canada , NPRP9-144-3-021 from Qatar Foundation , QUUG-CENG-MIE-15/16-7 and QUST-CENG-FALL-15/16-20 from Qatar University , the Farouk Jabre interdisciplinary research award from American University of Beirut , and the CNRS grant from National Council for Scientific Research, Lebanon , for the support for this paper.
اللغةen
الناشرElsevier Ltd
الموضوعHeart valves
Hydrogels
Microtechnologies
Nanotechnologies
Scaffolds
Tissue engineering
العنوانMicro and nanotechnologies in heart valve tissue engineering
النوعArticle Review
الصفحات278-292
رقم المجلد103
dc.accessType Abstract Only


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