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AuthorReddy, M. Sai Bhargava
AuthorPonnamma, Deepalekshmi
AuthorChoudhary, Rajan
AuthorSadasivuni, Kishor Kumar
Available date2022-03-23T06:35:47Z
Publication Date2021
Publication NamePolymers
ResourceScopus
Identifierhttp://dx.doi.org/10.3390/polym13071105
CitationReddy, M.S.B.; Ponnamma, D.; Choudhary, R.; Sadasivuni, Kishor Kumar A Comparative Review of Natural and Synthetic Biopolymer Composite Scaffolds. Polymers 2021, 13, 1105. https://doi.org/10.3390/polym13071105
URIhttp://hdl.handle.net/10576/28581
AbstractTissue engineering (TE) and regenerative medicine integrate information and technology from various fields to restore/replace tissues and damaged organs for medical treatments. To achieve this, scaffolds act as delivery vectors or as cellular systems for drugs and cells; thereby, cellular material is able to colonize host cells sufficiently to meet up the requirements of regeneration and repair. This process is multi-stage and requires the development of various components to create the desired neo-tissue or organ. In several current TE strategies, biomaterials are essential components. While several polymers are established for their use as biomaterials, careful consideration of the cellular environment and interactions needed is required in selecting a polymer for a given application. Depending on this, scaffold materials can be of natural or synthetic origin, degradable or nondegradable. In this review, an overview of various natural and synthetic polymers and their possible composite scaffolds with their physicochemical properties including biocompatibility, biodegradability, morphology, mechanical strength, pore size, and porosity are discussed. The scaffolds fabrication techniques and a few commercially available biopolymers are also tabulated.
SponsorFunding: The author, R. Choudhary, gratefully acknowledges the financial support from the European Union?s Horizon 2020 research and innovation program under the grant agreement No. 857287. The author presents sincere thanks to the Ministry of Science and Higher Education of the Russian Federation in the framework of the ?Increase Competitiveness? Program of National University of Science and Technology (NUST) �MISiS�, Moscow, Russia, for providing the financial help to carry out this research. This publication was also supported by Qatar University internal grant No. IRCC-2020-013. The findings herein are solely the responsibility of the authors.
Languageen
PublisherMDPI AG
SubjectBiodegradability
Natural biopolymer
Scaffolds
Synthetic biopolymer
Tissue engineering
TitleA comparative review of natural and synthetic biopolymer composite scaffolds
TypeArticle Review
Issue Number7
Volume Number13
dc.accessType Open Access


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