ماجستير في الصيدلة
التسجيلات التي قمت بإرسالها
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Combination of Curcumin and Cisplatin Induces Apoptosis and Anti-migration Effect in Lung Adenocarcinoma through AKT/mTOR Pathway and Independent of MAPK (ERK/RSK) pathway in Vitro
(2026 , Master Thesis)Background: Lung cancer is a leading cause of mortality worldwide. Cisplatin is one of the most common anti-cancer drugs. However, cisplatin loses its sensitivity in the late stages of cancer and has severe side effects. ... -
UNDERSTANDING THE ROLE OF SESTRIN2 IN ANGIOGENESIS AND RISK OF ISCHEMIC DISEASES ASSOCIATED WITH DIABETES: AN IN-VITRO STUDY AND HUMAN INVESTIGATION IN PARTICIPANTS OF QATAR BIOBANK
(2026 , Dissertation)Diabetes mellitus and cardiovascular disease represent converging global epidemics, primarily driven by diabetes-induced endothelial dysfunction and impaired reparative angiogenesis. The stress-inducible protein Sestrin2 ... -
PHARMACOPHORE-GUIDED VIRTUAL SCREENING FOR DRUG REPURPOSING AND BENZOFURAN LEAD OPTIMIZATION TOWARD SELECTIVE ALLOSTERIC MODULATION OF PROTEIN TYROSINE PHOSPHATASE 1B (PTP1B)
(2026 , Master Thesis)Protein Tyrosine Phosphatase 1B (PTP1B) is a key negative regulator of insulin and leptin signaling and plays a central role in the development of insulin resistance and associated cardiometabolic disorders. Although PTP1B ... -
CYTOCHROME P450 3A5 (CYP3A5) GENOTYPE-GUIDED DOSING OF TACROLIMUS IN KIDNEY TRANSPLANTATION IN QATAR: A COST-EFFECTIVENESS ANALYSIS
(2026 , Master Thesis)Objective: To summarize the evidence from the literature on the impact of various genotypes on tacrolimus pharmacokinetic and clinical outcomes in kidney transplant recipients, and to evaluate the cost effectiveness of a ... -
IMPACT OF MEDICATION BURDEN AND MEDICATION REGIMEN COMPLEXITY ON GLYCEMIC CONTROL AMONG PATIENTS WITH DIABETES
(2026 , Master Thesis)Diabetes mellitus represents a major global health challenge, with poor glycemic control being highly prevalent despite therapeutic advancements. The increasing complexity of medication regimens, often driven by polypharmacy ... -
THE MOLECULAR MECHANISMS UNDERPINNING THE ROLE OF SESTRIN 2 IN ENDOTHELIAL FUNCTION
(2025 , Dissertation)Cardiovascular diseases (CVD) associated with diabetes persist to be a major cause of death worldwide. Endothelial dysfunction (ED), a condition characterized by impaired Nitric Oxide (NO) bioavailability in endothelial ... -
IN VIVO BIODISTRIBUTION AND TOXICITY ASSESSMENT OF PEGYLATED GOLD AND SILVER NANOPARTICLES: INDIVIDUAL VERSUS CO-ADMINISTRATION VIA INTRAVENOUS ROUTE
(2025 , Master Thesis)Gold (AuNPs) and silver (AgNPs) nanoparticles (NPs) have drawn significant attention in biomedical research due to their distinctive physicochemical properties, which govern their biological interactions. A comprehensive ... -
TARGETING ENDOTHELIAL-TO-MESENCHYMAL TRANSITION IN DOXORUBICIN-INDUCED CARDIOVASCULAR TOXICITY: THE ROLE OF CYP EPOXYGENASES AND SOLUBLE EPOXIDE HYDROLASE/CYCLOOXYGENASE-2 INHIBITION
(2025 , Master Thesis)Background: Doxorubicin (DOX) is an anthracycline widely used against many neoplastic diseases. However, the clinical use of DOX is limited due to its dose-dependent cardiovascular toxicity. Recent studies suggest that ... -
CLINICAL VERSUS FIXED WARFARIN DOSING AND THE ADDED EFFECT OF A GENOTYPE GUIDED ALGORITHM ON WARFARIN DOSE PREDICTION IN ARABS
(2025 , Dissertation)Warfarin prescribing has been a challenge due to the need for frequent monitoring. Commonly, warfarin is prescribed using a fixed warfarin dosing method (FWD). Genotype guide warfarin dosing (GWD) is a method that uses ... -
EVALUATING PHARMACEUTICAL EDUCATION SITUATION IN THE EASTERN MEDITERRANEAN REGION USING THE INTERNATIONAL PHARMACEUTICAL FEDERATION'S DEVELOPMENT GOALS OF ACADEMIC CAPACITY AND QUALITY ASSURANCE
(2025 , Master Thesis)Introduction: The pharmaceutical workforce intelligence involves the development, implementation, and evaluation of effective strategies and tools to ensure the availability and quality of the pharmaceutical workforce. ... -
EXPLORING REPORTING OF MEDICATION ERRORS AT THE NATIONAL CENTER FOR CANCER CARE AND RESEARCH
(2025 , Master Thesis)Objectives: The objectives were to (a) examine the medication error reporting literature and synthesize existing studies to identify key factors affecting reporting practices; (b) quantify the prevalence , nature, and ... -
IMPLEMENTING LEARNING FROM CONTINUOUS PROFESSIONAL DEVELOPMENT ACTIVITIES: A QUALITATIVE STUDY OF PHARMACISTS AND NURSES' BEHAVIORS USING COM-B AND TDF
(2025 , Master Thesis)Introduction: Continuing Professional Development (CPD) is an approach for health professionals to maintain knowledge and competence and can contribute to improving delivery of care. However, there is a lack of studies ... -
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL CHALCONE ANALOGS AS POTENTIAL THERAPEUTIC AGENTS FOR CASTRATION RESISTANT PROSTATE CANCER
(2021 , Master Thesis)Prostate cancer (PCa) is the second most frequently diagnosed malignancy, as well as a leading cause of cancer-related mortality in men globally. Despite the initial response to hormonal targeted therapy, the majority of ... -
COST-EFFECTIVENESS ANALYSIS OF SUBCUTANEOUS DARATUMUMAB VERSUS INTRAVENOUS DARATUMUMAB IN NEWLY DIAGNOSED MULTIPLE MYELOMA
(2024 , Master Thesis)Background: Both subcutaneous (SC) and intravenous (IV) formulations of Daratumumab (Dara) are used, in combination with lenalidomide, bortezomib, and dexamethasone (VRd), for treating newly diagnosed multiple myeloma ... -
CURCUMIN-CONJUGATED CHITOSAN OLIGOMERS DERIVED FROM MICROWAVE IRRADIATION FOR NANOFORMULATION IN COLON CANCER TREATMENT
(2024 , Master Thesis)Colon cancer remains as one of the leading causes of deaths worldwide, whilst current treatment options are not optimal. Chemotherapy is the mainstay in cancer therapy but is associated with severe side effects. Some ... -
APPLICATION OF SOLID DISPERSION IN CONJUNCTION WITH 3D PRINTING FOR PERSONALIZED MEDICINE
(2024 , Master Thesis)Poorly water-soluble drugs accounts for 40% of the newly discovered APIs due to their lipophilic nature. Hence, to benefit from the therapeutic effects of such drugs requires administration of higher doses. However, ... -
THE EFFECT OF OBESITY ON RIVAROXABAN PHARMACOKINETICS AND PHARMACODYNAMICS
(2024 , Dissertation)Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a prevalent condition that is associated with high rates of morbidity and mortality worldwide. Similarly, atrial fibrillation ... -
INVESTIGATING THE ROLE OF THE ARYL HYDROCARBON RECEPTOR AND BCL-2 FAMILY PROTEINS IN OVARIAN CANCER STEM CELLS DEVELOPMENT AND CHEMORESISTANCE
(2024 , Dissertation)Gynecological malignancies are a severe threat to female health. Ovarian Cancer (OC), the most lethal gynecological malignancy, is clinically presented with chemoresistance and a higher relapse rate. This could be endorsed ... -
ECONOMIC EVALUATION OF DIABETIC NEUROPATHY MONOTHERAPY FOLLOWED BY COMBINATION THERAPY TREATMENT
(2024 , Master Thesis)Objective: To summarize the literature evidence towards the efficacy and safety of diabetic neuropathy (DNP) treatments, and to assess the cost-effectiveness among the DNP treatment regimens in Qatar, including the use of ... -
The Cytotoxicity Of “Al-Siddir” Tree “Ziziphus Spina Christi” Methanolic Leaves Extract on Her-2 Positive Breast Cancer
(2024 , Master Thesis)HER-2 positive is a subtype of breast cancer that acquires poor prognosis and low survival rates. Targeted therapy is one of the main approaches that are used for the treatment of HER-2-positive breast cancer. However, it ...
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