أبحاث الطب
التسجيلات التي قمت بإرسالها
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A HORMONAL AND CLINICAL INVESTIGATION OF SURGICAL FAT REMOVAL
(2026 , Dissertation)Obesity remains one of the most pressing global health challenges, with Qatar among the most affected regions. While bariatric surgery is well established for inducing durable weight loss, and newer pharmacologic agents ... -
EXPLORING NEW THERAPEUTIC AVENUES AGAINST HER2-POSITIVE BREAST CANCER
(2025 , Dissertation)HER2-positive breast cancer (BC) is a challenging disease characterized by poor prognosis, relapses, and aggressive behavior in the tumor. HER2 oncoprotein dimerization with other growth factor receptor family members ... -
POST-TRANSLATIONAL MODIFICATIONS IN CANCER AND DIABETES
(2025 , Dissertation)Background: In Qatar, non-communicable diseases like cancer and diabetes are leading causes of mortality. Cancer is caused by various environmental and hereditary factors, with metastasis from the primary site being the ... -
VASCULAR REMODELING IN HYPERTENSION: IN-VITRO/ EX-VIVO MECHANICAL STRETCH-INDUCED ALTERATIONS AND OMICS ANALYSIS
(2024 , Dissertation)Hypertension, being a primary vasculature disorder, contributes significantly to premature death globally. Over the years, numerical figures have evidenced a dramatic increase in hypertension’s global prevalence, affecting ... -
INVESTIGATING THE MOLECULAR MECHANISMS OF SHEAR STRESS INDUCED ENDOTHELIAL DYSFUNCTION AND PROGRESSION OF ATHEROSCLEROSIS
(2024 , Dissertation)Background: Atherosclerotic vascular disease, such as coronary artery disease (CAD) and ischemic stroke is the leading cause of mortality and disability worldwide. Therefore, understanding the mechanisms underlying ... -
STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
(2024 , Dissertation)Homocystinuria, a rare disorder stemming from mutations in the CBS gene, results in cystathionine β-synthase (CBS) deficiency. CBS is a pivotal enzyme whose activity is enhanced by the allosteric regulator S-adenosylmethionine ... -
Co-Presence and Cooperation of High-Risk Human Papillomaviruses and Epstein-Barr Virus in Colorectal Cancer
(2024 , Dissertation)The Human Papillomavirus (HPV) and Epstein-Barr Virus (EBV) are potent oncoviruses involved in the pathogenesis of various cancers like colorectal cancer. Further the cooperation between high risk (HR) types of HPV as well ... -
METABOLIC CHANGES AFTER SURGICAL SUBCUTANEOUS FAT REMOVAL
(2023 , Dissertation)Background: There is increasing demand for both surgical (SSFR) and nonsurgical (NSSFR) subcutaneous fat removal procedures for achieving immediate improvements in physical appearance. However, their metabolic effects ... -
Vitamin D Immune Modulatory Effect on the Anti-inflammatory potential of HDL Associated Proteins
(2023 , Dissertation)Introduction: Vitamin D deficiency is highly prevalent in Qatar. Vitamin D exerts immune-modulatory effects leading to reduced inflammation. Therefore, vitamin D deficiency is associated with increased subclinical inflammation. ... -
DEVELOPMENT OF A PROBLEM AND ATTRIBUTES BASED DIABETES SELF-MANAGEMENT (PARADIGM) INTERVENTION
(2022 , Dissertation)Background: Type 2 diabetes mellitus (T2D), is a growing pandemic across the world. T2D requires a comprehensive diabetes self-management (DSM) skills in addition to medications. It is still unclear what interventions can ...
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