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AuthorDong S.
AuthorMesbah M.
AuthorLingwood B.E.
AuthorO'Toole J.M.
AuthorBoashash B.
Available date2022-05-31T19:01:40Z
Publication Date2011
Publication NameComputing in Cardiology
ResourceScopus
URIhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84859939363&partnerID=40&md5=24a895525f2b837fa17db33ee3c651eb
URIhttp://hdl.handle.net/10576/31940
AbstractTo determine whether the sympathetic nervous system plays any role in the inter-individual variation of cardiovascular response to hypoxia in newborns, neonatal heart rate variability (HRV) analysis was used to assess autonomic response during hypoxia in piglets. Due to the nonstationary nature of HRV signals and the inaccuracy in pre-defined neonatal HRV frequency bands using standard spectral methods, we applied time-frequency distribution analysis to assess neonatal HRV. Although sympathetic activity was initially enhanced to stimulate the cardiac compensation, it did not account for the variation of cardiovascular response since the power of low frequency component in HRV neither showed corresponding changes with the heart rate nor had any correlation with the brain injury. This may be attributed to immaturity of the neural pathway.
Languageen
SubjectBrain injury
Heart rate variability
Heart rates
Low-frequency components
Neural pathway
Nonstationary
Spectral methods
Sympathetic activities
Sympathetic nervous systems
Time frequency analysis
Time-frequency distributions
Cardiology
Frequency bands
Heart
Pediatrics
TitleTime-frequency analysis of heart rate variability in neonatal piglets exposed to hypoxia
TypeConference Paper
Pagination701-704
Volume Number38
dc.accessType Abstract Only


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