Student Thesis & Dissertations: Recent submissions
Now showing items 121-140 of 1639
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ECONOMIC EVALUATION OF DIABETIC NEUROPATHY MONOTHERAPY FOLLOWED BY COMBINATION THERAPY TREATMENT
(2024 , Master Thesis)Objective: To summarize the literature evidence towards the efficacy and safety of diabetic neuropathy (DNP) treatments, and to assess the cost-effectiveness among the DNP treatment regimens in Qatar, including the use of ... -
CURCUMIN-CONJUGATED CHITOSAN OLIGOMERS DERIVED FROM MICROWAVE IRRADIATION FOR NANOFORMULATION IN COLON CANCER TREATMENT
(2024 , Master Thesis)Colon cancer remains as one of the leading causes of deaths worldwide, whilst current treatment options are not optimal. Chemotherapy is the mainstay in cancer therapy but is associated with severe side effects. Some ... -
APPLICATION OF SOLID DISPERSION IN CONJUNCTION WITH 3D PRINTING FOR PERSONALIZED MEDICINE
(2024 , Master Thesis)Poorly water-soluble drugs accounts for 40% of the newly discovered APIs due to their lipophilic nature. Hence, to benefit from the therapeutic effects of such drugs requires administration of higher doses. However, ... -
IDENTIFICATION AND FUNCTIONAL VALIDATION OF RARE MISSENSE VARIANTS IN PLXNA1 AS A CANDIDATE GENE FOR SEVERE EARLY-ONSET OBESITY
(2024 , Master Thesis)Childhood obesity is a pressing issue in Qatar, with a reported prevalence of 49% among school-aged children and adolescents. This complex problem involves a combination of genetic and environmental factors. Monogenic ... -
GENETIC CAUSES OF CARDIAC CHANNELOPATHIES IN QATAR: TOWARD RISK STRATIFICATION AND MANAGEMENT STRATEGIES OF DISEASE
(2024 , Professional Masters Project)Background: Cardiac channelopathies are inherited disorders caused by pathogenic variants in genes encoding cardiac ion channels, disrupting ion currents, and leading to heart arrhythmias without structural heart defects. ... -
QATAR NATIONAL EXPANDED METABOLIC NEWBORN SCREENING PROGRAM: INCIDENCE AND OUTCOMES
(2024 , Professional Masters Project)Background: Newborn screening (NBS) is an essential public health strategy that aims to detect and diagnose inborn errors of metabolism (IEMs) in infants shortly after birth, typically through a minimally invasive heel ... -
RELATION BETWEEN BREAST MILK CONTENT OF TOTAL AFLATOXIN AND SOCIODEMOGRAPHIC AND NUTRITIONAL STATUS OF LACTATING MOTHERS IN QATAR
(2024 , Master Thesis)Background: Human milk is the ideal nourishment for neonates, as its unique nutritional composition supports adequate growth and development. On the other hand, human milk might contain contaminants including aflatoxins ... -
CHARACTERIZATION OF PATHOGEN-ASSOCIATED ANTIBODY PROFILES IN DIABETES MELLITUS-TYPE 2 PATIENTS USING IMMUNOPROTEOMICS APPROACH
(2024 , Master Thesis)Type 2 diabetes mellitus (T2DM) is a common health concern globally. 80% of diabetic patients are T2DM patients. T2DM can result in many serious complications. For instance, cardiovascular diseases, renal diseases, eye ... -
INVESTIGATING THE MOLECULAR MECHANISMS OF SHEAR STRESS INDUCED ENDOTHELIAL DYSFUNCTION AND PROGRESSION OF ATHEROSCLEROSIS
(2024 , Dissertation)Background: Atherosclerotic vascular disease, such as coronary artery disease (CAD) and ischemic stroke is the leading cause of mortality and disability worldwide. Therefore, understanding the mechanisms underlying ... -
THE EFFECT OF OBESITY ON RIVAROXABAN PHARMACOKINETICS AND PHARMACODYNAMICS
(2024 , Dissertation)Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a prevalent condition that is associated with high rates of morbidity and mortality worldwide. Similarly, atrial fibrillation ... -
UNRAVELING THE MICROBIOME DIVERSITY AND DYNAMICS IN DIFFERENT SAMPLE TYPES DURING CORONAVIRUS INFECTIONS
(2024 , Master Thesis)Background: Mucosal immunity and gut microbiome influence respiratory diseases like those caused by coronaviruses (HCoV). This study explores the relationship between HCoV infection and the respiratory and gut microbiome. ... -
ASSOCIATION BETWEEN SOCIO-DEMOGRAPHICS AND NUTRITION KNOWLEDGE IN RELATION TO DIETARY ADHERENCE AND METABOLIC CONTROL IN HOMOCYSTINURIA PATIENTS IN QATAR
(2024 , Master Thesis)Classical Homocystinuria (HCU) is a metabolic disorder characterized by disrupted methionine metabolism, resulting in elevated homocysteine levels and potential organ complications. Understanding treatment adherence's ... -
PRENATAL WHOLE EXOME SEQUENCING OF FETAL SONOGRAPHIC ABNORMALITIES IN QATAR: DIAGNOSTIC YIELD AND GENETIC FINDINGS
(2024 , Professional Masters Project)Background: Fetal sonographic abnormalities at birth is estimated to be 2-3% of the global prevalence and are responsible for approximately 17%-42% of all perinatal deaths. Prenatal karyotype (KT) and chromosomal microarray ... -
ASSESSMENT OF GNAS LOSS OF FUNCTION IN MONOGENIC OBESITY USING THE ZEBRAFISH MODEL
(2024 , Master Thesis)GNAS (Guanine Nucleotide-Binding Protein, Alpha Stimulating) is an imprinted gene that encodes the alpha subunit of the stimulatory G protein (Gs), which participates in the signaling of various G protein-coupled receptors. ... -
ASSESSMENT OF DIETARY HABITS, PHYSICAL ACTIVITY, LIFESTYLE, AND OTHER RISK FACTORS OF NONALCOHOLIC FATTY LIVER DISEASE AMONG ARAB ADULTS LIVING IN QATAR
(2024 , Master Thesis)Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is defined as an abnormal accumulation of triglycerides in the liver. It is the most common chronic liver disease globally and is linked to ... -
ANALYSIS OF MUTATIONS USING ANCIENT DNA GENOMES TO UNDERSTAND PATHOGENIC EMERGENCE AND DISEASE EVOLUTION
(2024 , Master Thesis)Paleogenomics, the study of ancient DNA, has revolutionized our comprehension of human history by providing access to genomic data spanning hundreds of thousands of years. High-throughput sequencing methods have enabled ... -
Dissecting the Role of Physical Activity and Sleep in Metabolically Healthy Obese Subjects: A National Study
(2024 , Master Thesis)In the last decade, researchers brought attention to a subgroup of obesity that has a lower risk of cardiometabolic abnormalities. Considering Qatar is one of the top-ranked countries in terms of obesity, this study aims ... -
TRANSLATION AND ADAPTATION OF THE GENETIC COUNSELING OUTCOME SCALE (GCOS-24) FOR THE EVALUATION OF GENETIC COUNSELING SERVICES IN QATAR.
(2024 , Professional Masters Project)Background. The Genetic Counseling Outcome Scale (GCOS-24), introduced in the United Kingdom (UK) in 2011, is a theory-driven patient-reported outcome measure (PROM) developed for evaluating clinical genetics services. ... -
THE EFFECT OF GENERATIVE AI ON STUDENTS' CREATIVE PROBLEM-SOLVING SKILLS
(2024 , Master Thesis)Higher Education Institutions (HEI) are assigned the responsibility of cultivating skillsets in students that improve their employability and maximize their value to industry. Creativity and problem-solving are important ... -
EXPLORING THE FACTORS THAT IMPACT THE DECISION TO START A NEW VENTURE: THE CASE OF WOMEN IN QATAR
(2024 , Professional Masters Project)As the female entrepreneur population in Qatar grows, their contributions to the economy have increased. Despite extensive research on general factors impacting entrepreneurial ventures, specific factors influencing female ...
