Show simple item record

AuthorJiang, Ke
AuthorXie, Changxiao
AuthorLi, Zhourong
AuthorZeng, Huan
AuthorZhao, Yong
AuthorShi, Zumin
Available date2022-09-21T06:01:57Z
Publication Date2022-08-01
Publication NameNutrients
Identifierhttp://dx.doi.org/10.3390/nu14153005
CitationJiang, K.; Xie, C.; Li, Z.; Zeng, H.; Zhao, Y.; Shi, Z. Selenium Intake and its Interaction with Iron Intake Are Associated with Cognitive Functions in Chinese Adults: A Longitudinal Study. Nutrients 2022, 14, 3005. https://doi.org/10.3390/nu14153005
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85135101691&origin=inward
URIhttp://hdl.handle.net/10576/34242
AbstractStudies on the relation between selenium intake and cognitive function are inconclusive. This study aimed to examine the associations between dietary selenium intake and cognitive function among Chinese adults and tested the interaction effect of selenium intake and iron intake on cognition. Data from 4852 adults aged 55 years and above who attended the 1991–2006 China Health and Nutrition Survey (CHNS) were used. Cognitive function was assessed through face-to-face interviews in 1997, 2000, 2004, and 2006. A 3-day, 24-hour recall was used to collect dietary selenium intake. Multivariable mixed linear regression and logistic regression were used in the analyses. In fully adjusted regression models, the regression coefficients (95% confidence interval) were 0.00, 0.29 (−0.12–0.70), 0.26 (−0.18–0.70), and 0.50 (0.02–0.97) across the quartiles of selenium intake. In the subgroup analysis, the positive association between selenium intake and cognitive function was only observed in the participants who live in the southern region but not those in the northern region. The selenium-intake-to-iron-intake ratio was inversely associated with low global cognition scores. Furthermore, only those with a normal BMI had a positive association between selenium and cognition. In conclusion, high selenium intake was linked to better cognitive function and a lower risk of cognition decline in Chinese adults among those with low iron intake. A substantial interaction was found between selenium intake and BMI or region.
SponsorThisproject wasfundedbytheprojectofChongqingNutritionSociety(2019001)-Research on dietary selenium intake and its relationship with hypertension and diabetes in middle-aged and older adults in Jiangjin Chongqing. Thefundershadnoroleinthedesign, analysis, datainterpretation, and publication of the findings.
Languageen
PublisherMDPI
Subjectadults
Chinese
cognitive function
iron intake
nutrition survey
selenium intake
TitleSelenium Intake and its Interaction with Iron Intake Are Associated with Cognitive Functions in Chinese Adults: A Longitudinal Study
TypeArticle
Issue Number15
Volume Number14
ESSN2072-6643
dc.accessType Open Access


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record