Browsing Chemistry & Earth Sciences by Author "Griffith, Darren M."
Now showing items 1-1 of 1
-
A novel platinum complex of the histone deacetylase inhibitor belinostat: Rational design, development and in vitro cytotoxicity
Parker, James P.; Nimir, Hassan; Griffith, Darren M.; Duff, Brian; Chubb, Anthony J.; Brennan, Marian P.; Morgan, Maria P.; Egan, Denise A.; Marmion, Celine J.... more authors ... less authors ( Elsevier Inc. , 2013 , Article)The successful design and synthesis of a novel Pt complex of the histone deacteylase inhibitor belinostat are reported. Molecular modelling assisted in the identification of a suitable malonate derivative of belinostat(mal-p-Bel) ...