Browsing Research Units by Title
Now showing items 3545-3564 of 4709
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The role of CD44, hyaluronan and NHE1 in cardiac remodeling.
( Elsevier , 2018 , Article)Cardiac remodeling, characterized by excessive extracellular matrix (ECM) remodeling, predisposes the heart to failure if left unresolved. Understanding the signaling mechanisms involved in excessive extracellular matrix ... -
The Role of Epstein-Barr Virus in Cervical Cancer: A Brief Update.
( Frontiers Media , 2018 , Article Review)Epstein-Barr virus (EBV) belongs to the group of gamma-herpes viruses and was the first recognized human oncovirus. EBV is responsible for infectious mononucleosis and multiple lymphoid and epithelial malignancies including ... -
The role of genetic and epigenetic GNAS alterations in the development of early-onset obesity
( Elsevier , 2023 , Article)BackgroundGNAS (guanine nucleotide-binding protein, alpha stimulating) is an imprinted gene that encodes Gsα, the α subunit of the heterotrimeric stimulatory G protein. This subunit mediates the signalling of a diverse ... -
Role of genetics in eleven of the most common autoimmune diseases in the post genome-wide association studies era
( Verduci Editore s.r.l , 2023 , Article)Autoimmune diseases (ADs) are common conditions in which an individual’s immune system reacts against its healthy cells. This condition is a common cause of morbidity and mortality, with an estimated prevalence ranging ... -
Role of Graphene Oxide in Bacterial Cellulose−Gelatin Hydrogels for Wound Dressing Applications
( American Chemical Society , 2022 , Article)Biopolymer-based hydrogels have several advantages, including robust mechanical, high biocompatibility, and excellent properties. These hydrogels can be ideal wound dressing materials and advantageous to repair and regenerate ... -
Role of HMGB1 and its associated signaling pathways in human malignancies
( Elsevier , 2023 , Article)The High-Mobility Group Box-1 (HMGB1), a non-histone chromatin-associated protein, plays a crucial role in cancer growth and response to therapy as it retains a pivotal role in promoting both cell death and survival. HMGB1 ... -
Role of Inflammatory Cytokines, Growth Factors and Adipokines in Adipogenesis and Insulin Resistance
( Springer , 2021 , Article Review)Obesity, manifested by increased adiposity, represents a main cause of morbidity in the developed countries, causing increased risk of insulin resistance and type 2 diabetes mellitus. Recruitment of macrophages and activation ... -
Role of metal oxide nanofibers in water purification
( Elsevier , 2021 , Book chapter)Water treatment through nanomaterials and nanocomposites is a booming research area, since water resources are of prime importance for human sustainability. Having high permeability, optimum pore size, and specific surface ... -
The Role of Multidisciplinary Chemistry Informal Research Programs in Building Research Competencies and Attitudes
( American Chemical Society , 2022 , Article)This article is focused on the effectiveness of an innovative research-based learning model that employs chemistry-based research projects in developing high school students' research competency and attitudes. The ... -
Role of NAD+ in regulating cellular and metabolic signaling pathways
( Elsevier , 2021 , Article Review)BackgroundNicotinamide adenine dinucleotide (NAD+), a critical coenzyme present in every living cell, is involved in a myriad of metabolic processes associated with cellular bioenergetics. For this reason, NAD+ is often ... -
Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance.
( BMC , 2020 , Article Review)Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients. The factors limiting the current screening approaches to leukemia ... -
Role of organic cation in modern lead-based perovskites
( Elsevier Ltd , 2019 , Article)Hybrid organic-inorganic metal perovskites (ABX3, A- organic cation, B-metal ion, X-halide ion) have shown significant potential as thin-film solar cells or Dye solar cells (DSC) materials. Using a time-dependent density ... -
The Role of p90 Ribosomal S6 Kinase (RSK) in Tyrosine Kinase Inhibitor (TKI)-Induced Cardiotoxicity
( Springer , 2023 , Article Review)Targeted therapy, such as tyrosine kinase inhibitors (TKIs), has been approved to manage various cancer types. However, TKI-induced cardiotoxicity is a limiting factor for their use. This issue has raised the need for ... -
The role of polypropylene microfibers in thermal properties and post-heating behavior of cementitious composites
( Multidisciplinary Digital Publishing Institute (MDPI) , 2020 , Article)This paper experimentally studied the effect of polypropylene (PP) microfibers on thermal and post-heating mechanical behaviors of cementitious composites. Cement mortars with small dosage of polypropylene fibers were ... -
Role of Qat chewing and mate consumption in human oral carcinogenesis
( Springer International Publishing , 2017 , Book chapter)[No abstract available] -
The role of religiosity types in the phenomenology of hallucinations: A large cross-sectional community-based study in a predominantly Muslim society
( Elsevier , 2022 , Article)Religiosity is a multidimensional construct known to influence the occurrence of hallucinations. However, it remains unknown how different religiosity types affect clinically relevant phenomenological features of hallucinations. ... -
Role of Research and Higher Education on Industry 4.0, Material Science as an example
( Institute of Electrical and Electronics Engineers Inc. , 2020 , Conference Paper)Industry 4.0 is changing the world. Higher education institutes are contributing to these changes through research and education. This paper sheds light on materials science as a critical component in the fourth industrial ... -
Role of RhoA and Rho-associated kinase in phenotypic switching of vascular smooth muscle cells: Implications for vascular function
( Elsevier , 2022 , Article Review)Cardiovascular disease (CVD) continues to be the primary cause of global mortality. Vascular smooth muscle cells (VSMCs) are integral components of vascular structure and function, evident by their vital roles in modulating ... -
Role of shamal and easterly winds on the wave characteristics off Qatar, central Arabian Gulf
( Elsevier , 2021 , Article)Waves in the Arabian Gulf (Gulf) are dominated by shamal winds during winter and early summer. Although wave characteristics in the Gulf are broadly studied, features associated with various wind systems are not explicitly ... -
The role of social networks in the formation of transnational higher education partnership: a case study of a British university and a Qatari education institute
( Taylor and Francis Group , 2024 , Article)Transnational higher education (TNE) became the dominant higher education arrangement in the Middle East. This article reports on the role of individuals in setting up TNE partnerships between a Qatari educational institute ...