College of Pharmacy: المرسلات الحديثة
السجلات المعروضة 1041 -- 1060 من 1280
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Protein expression profiling identifies key proteins and pathways involved in growth inhibitory effects exerted by guggulsterone in human colorectal cancer cells
( MDPI AG , 2019 , Article)Colorectal cancer (CRC) is a leading killer cancer worldwide and one of the most common malignancies with increasing incidences of mortality. Guggulsterone (GS) is a plant sterol used for treatment of various ailments such ... -
Self-reported attitudes and perceived preparedness to provide pharmaceutical care among final year pharmacy students in Qatar and Kuwait
( International Pharmaceutical Federation , 2018 , Article)Purpose: While pharmaceutical care (PC) had been introduced and taught in schools of pharmacy decades ago, it is still being introduced with different degrees of success in many developing countries around the world. This ... -
General public and community pharmacists perception on counterfeit medicines: A preliminary cross-sectional study in Qatar
( Journal of Clinical and Diagnostic Research , 2018 , Article)Introduction: One major contributing factor to the prevalence of counterfeit medicines in a country is the lack of knowledge and awareness of the society. Information on general public and healthcare professionals awareness ... -
Quality of Pharmacy Health Services
( Elsevier Inc. , 2018 , Book chapter)The quality of pharmacy health services can only be assured by the presence of qualified and competent pharmacists. In developing countries, healthcare facilities are insufficient for providing good-quality health services ... -
Communicating medication risk to cardiovascular patients in Qatar
( Emerald Group Publishing Ltd. , 2018 , Article)Purpose: Patient safety is gaining prominence in health professional curricula. Patient safety must be complemented by teaching and skill development in practice settings. The purpose of this paper is to explore how ... -
The effect of genetic and nongenetic factors on warfarin dose variability in Qatari population.
( Pharmacogenomics Journal , 2020 , Article)The objective of this study is to estimate the prevalence of VKORC1, CYP2C9, and CYP4F2 genetic variants and their contribution to warfarin dose variability in Qataris. One hundred and fifty warfarin-treated Qatari patients ... -
Pharmacogenomics In Pharmacy Practice: Current Perspectives.
( Dove Medical Press , 2019 , Article)Pharmacogenomics (i.e., the application of genetic information in predicting an individual's response to drug therapy) plays an increasingly important role in drug development and decision-making regarding precision medicine. ... -
Economic Evaluations of CYP2C19 Genotype-Guided Antiplatelet Therapy Compared to the Universal Use of Antiplatelets in Patients With Acute Coronary Syndrome: A Systematic Review.
( SAGE Publications , 2020 , Article)Clopidogrel is widely used after the percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS) and requires activation by cytochrome P450 (CYP), primarily CYP2C19. Patients with CYP2C19 ... -
Phloretin attenuates STAT-3 activity and overcomes sorafenib resistance targeting SHP-1-mediated inhibition of STAT3 and Akt/VEGFR2 pathway in hepatocellular carcinoma
( BioMed Central Ltd. , 2019 , Article)Background: Hepatocellular carcinoma (HCC) is the most common primary liver malignancy. Phloretin (PH) possesses anticancer, antitumor, and hepatoprotective effects, however, the effects and potential mechanisms of phloretin ... -
7-O-methylpunctatin, a novel homoisoflavonoid, inhibits phenotypic switch of human arteriolar smooth muscle cells
( MDPI AG , 2019 , Article)Remodeling of arterioles is a pivotal event in the manifestation of many inflammation-based cardio-vasculopathologies, such as hypertension. During these remodeling events, vascular smooth muscle cells (VSMCs) switch from ... -
A systematic review of audience response systems in pharmacy education
( Elsevier Inc. , 2019 , Article Review)Background: Audience response systems (ARS) are increasingly being used to support learning and assessment. Despite widespread use, the effects on educational outcomes and student learning are largely unknown. The objective ... -
CD56 expression in breast cancer induces sensitivity to natural killer-mediated cytotoxicity by enhancing the formation of cytotoxic immunological synapse
( Nature Publishing Group , 2019 , Article)We examined the potential value of the natural killer (NK) cell line; NK-92, as immunotherapy tool for breast cancer (BC) treatment and searched for biomarker(s) of sensitivity to NK-92-mediated cytotoxicity. The cytotoxic ... -
Assessment of Dapagliflozin Effectiveness as Add-on Therapy for the Treatment of Type 2 Diabetes Mellitus in a Qatari Population
( Nature Publishing Group , 2019 , Article)The effectiveness of dapagliflozin in the management of type-2 diabetes mellitus (T2-DM) is an essential issue for establishing a basis for prescribing dapagliflozin. This study aimed to assess the effectiveness of ... -
Optimizing assessors’ mental workload in rater-based assessment: a critical narrative review
( Bohn Stafleu van Loghum , 2019 , Article Review)Introduction Rater-based assessment has resulted in high cognitive demands for assessors within the education of health professionals. Rating quality may be influenced by the mental workload required of assessors to ... -
Measurement of health literacy in patients with cardiovascular diseases: A systematic review
( Elsevier Inc. , 2019 , Article Review)Background: While many instruments have been developed, validated, and used to assess health literacy skills, their use and appropriateness among patients with cardiovascular diseases (CVDs) are not widely studied. Objective: ... -
Cetuximab-conjugated chitosan-pectinate (modified) composite nanoparticles for targeting colon cancer
( Elsevier B.V. , 2019 , Article)In the present study, we successfully developed a cetuximab-conjugated modified citrus pectin-chitosan nanoparticles for targeted delivery of curcumin (Cet-MCPCNPs) for the treatment of colorectal cancer. In vitro analyses ... -
Relationship between pharmaceutical pricing strategies with price, availability, and affordability of cardiovascular disease medicines: Surveys in Qatar and Lebanon
( BioMed Central Ltd. , 2019 , Article)Background: Cardiovascular diseases are the leading cause of death in Lebanon and Qatar. When lifestyle modifications prove insufficient, medication becomes a cornerstone in controlling such diseases and saving lives. ... -
Development of injectable PEGylated liposome encapsulating disulfiram for colorectal cancer treatment
( MDPI AG , 2019 , Article)Disulfiram (DS), an anti-alcoholism medicine, shows strong anti-cancer activity in the laboratory, but the application in clinics for anti-cancer therapy has been limited by its prompt metabolism. Conventional liposomes ... -
AMP-activated protein kinase as a drug target in chronic kidney disease
( Bentham Science Publishers B.V. , 2018 , Article Review)Background: Chronic kidney disease (CKD) is a condition increasingly affecting millions of individuals worldwide and is ranked as the ninth leading cause of death in the United States. AMP-activated protein kinase (AMPK) ... -
The development of a theory-informed Communities of Practice Framework for pharmacy and other professional healthcare education programmes
( International Pharmaceutical Federation , 2018 , Article)This paper describes the development of a novel Communities of Practice (CoP) theory-informed framework. The CoP framework, developed through a rigorous process of extensive review of the literature and peer review by ...