College of Pharmacy: Recent submissions
Now showing items 1261-1280 of 1280
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Effect of serum lipoproteins on stereoselective halofantrine metabolism by rat hepatocytes
( John Wiley & Sons, Ltd , 2012 , Article)Experimental hyperlipidemia has shown to decrease cytochrome P450 3A4 and 2C11 expression and to increase liver concentrations and the plasma protein binding of halofantrine (HF) enantiomers. The present study examined the ... -
Impact of the CYP4F2 p.V433M Polymorphism on Coumarin Dose Requirement: Systematic Review and Meta-Analysis
( Nature Publishing Group , 2012 , Article)A systematic review and a meta-analysis were performed to quantify the accumulated information from genetic association studies investigating the impact of the CYP4F2 rs2108622 (p.V433M) polymorphism on coumarin dose ... -
Effect of hyperlipidemia on ketoconazole-midazolam drug-drug interaction in rat
( John Wiley & Sons, Ltd. , 2011 , Article)Hyperlipidemia (HL) was previously shown to lower liver uptake of the more potent (-) enantiomer of ketoconazole (KTZ) in rat. The current study examined the possible modifying influence of experimental HL on a KTZ ... -
Determination of the main factors contributing to increases in medicine expenditures for the National Health Insurance Fund in Sudan
( John Wiley & Sons Ltd , 2013 , Article)To assess the main factors that contributed to the increase in medicine expenditure of the National Health Insurance Fund in Sudan in the period 2006–2010. A time-series decomposition analysis was adopted for pharmaceutical ... -
Targeting Osteopontin, the Silent Partner of Na+/H+ Exchanger Isoform 1 in Cardiac Remodeling
( Wiley Periodicals, Inc. , 2015 , Article)Cardiac hypertrophy (CH), characterized by the enlargement of cardiomyocytes, fibrosis and apoptosis, contributes to cardiac remodeling, which if left unresolved results in heart failure. Understanding the signaling pathways ... -
Improving type 2 diabetes patients' quality of life by using a community based interactive approach – diabetes mellitus strategy in Yogyakarta, Indonesia
( Blackwell Publishing Ltd , 2012 , Article)The aim of this study was to improve diabetes patients' quality of life (QOL) by using a community based interactive approach – diabetes mellitus (CBIA-DM) strategy. This study was a time-series pre and post quasi-experimental ... -
Time to entry of generic medicines in Malaysia: implications for pharmaceutical cost containment
( John Wiley & Sons, Ltd , 2013 , Article)Generic medicine availability is crucial for maintaining the Malaysian heavily subsidised public healthcare system, and for reducing rising national pharmaceutical expenditure. This paper analyses the time to entry of ... -
Pharmacy student perceptions of public health service roles and responsibilities
( Blackwell Publishing Ltd , 2011 , Article)Background There is increasing emphasis on pharmacists' assuming responsibility for public health promotion and delivery with formal expansion of public health activities in their practice. A number of pharmacy school ... -
Impact of a pharmacy practice research capacity-building programme on improving the research abilities of pharmacists at two specialised tertiary care hospitals in Qatar: a preliminary study
( John Wiley & Sons, Ltd. , 2015 , Article)The aim of this study was to develop and implement a pharmacy practice research training programme and to determine the effect of the programme on pharmacists' knowledge of, and attitudes towards, research. An intensive ... -
Suitability of digoxin as a P-glycoprotein probe: Implications of other transporters on sensitivity and specificity
( John Wiley & Sons Ltd. , 2014 , Article)The study of transporter-mediated drug–drug interactions (DDI) requires use of appropriate probes to reflect transporter function. Digoxin is often used as a probe in DDI studies involving P-glycoprotein (P-gp) and is ... -
Provision of health /disease screening and medication monitoring /management in New Zealand community pharmacies
( Wiley Publishing Asia Pty Ltd , 2014 , Article)Access to health /disease screening (HDS) and medication monitoring /management (MM) services in New Zealand has traditionally been through general practitioners. While government and professional organisations are supportive ... -
Pharmacoeconomic analysis of voriconazole vs. caspofungin in the empirical antifungal therapy of febrile neutropenia in Australia
( Blackwell Publishing Ltd , 2012 , Article)In two major clinical trials, voriconazole and caspofungin were recommended as alternatives to liposomal amphotericin B for empirical use in febrile neutropenia. This study investigated the health economic impact of using ... -
Interleukin-2: Evaluation of routes of administration and current delivery systems in cancer therapy
( Wiley Subscription Services, Inc., A Wiley Company , 2009 , Article)Despite the fact that different administration routes and delivery systems have been used for interleukin-2 (IL-2) delivery, little has been reported regarding the most efficient strategies used to deliver IL-2 in a nontoxic, ... -
An inventory of diabetes care in Qatar
( John Wiley & Sons, Ltd. , 2011 , Article)Diabetes is a global epidemic and the highest prevalence rates in the world are found in Gulf Corporation Council countries, including Qatar. The country's Supreme Council of Health has recognised its significant health ... -
A survey on the awareness and attitude of pharmacists and doctors towards the application of pharmacogenomics and its challenges in Qatar
( John Wiley & Sons, Ltd. , 2015 , Article)RATIONALE, AIMS AND OBJECTIVES: Pharmacists are expected to play an important role in applying pharmacogenomics discoveries to patient care. Despite the increased attention to genetic research in Qatar, clinicians' attitudes ... -
Structured Multi-Skill Assessment (SMSA) in pharmacy: A contextual adaptation for authentic assessment for colleges of pharmacy and beyond
( Bloomsbury Qatar Foundation Journals , 2015 , Article)There is a need for a contextual adaptation model of the Objective Structured Clinical Examination (OSCE) procedures and assessment methods into diverse contexts with great cultural diversity that is both affordable and ... -
Incidence, severity and preventability of medication-related visits to the emergency department: A prospective study
( Canadian Medical Association , 2008 , Article)Background: Medication-related visits to the emergency department are an important but poorly understood phenomenon. We sought to evaluate the frequency, severity and preventability of drug-related visits to the emergency ... -
Assessing the responsiveness of the Asthma Quality of Life Questionnaire with pharmaceutical care
( Springer Netherlands , 2007 , Article)Objective: To assess the responsiveness of the Asthma Quality of Life Questionnaire (AQLQ) in the context of pharmaceutical care delivery New Zealand community pharmacy setting. Setting: Community pharmacy practices in ... -
Pharmacy education and practice in 13 middle eastern countries
( American Association of Colleges of Pharmacy , 2008 , Article)The Arab world has influenced the art and science of pharmacy for centuries. Pharmacy education and practice is continuing to evolve in the Arabic-speaking traditional Middle East countries, although relatively little ... -
Resident physician and hospital pharmacist familiarity with patient discharge medication costs
( Springer Netherlands , 2008 , Article)Objective Cost-related medication non-adherence is associated with increased health-care resource utilization and poor patient outcomes. Physicians-in-training generally receive little education regarding costs of prescribed ...