College of Pharmacy: Recent submissions
Now showing items 1181-1200 of 1280
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Temporal cross talk between endoplasmic reticulum and mitochondria regulates oxidative stress and mediates microparticle-induced endothelial dysfunction
( Mary Ann Liebert, Inc. , 2017 , Article)Aims: Circulating microparticles (MPs) from metabolic syndrome patients and those generated from apoptotic T-cells induce endothelial dysfunction; however, the molecular and cellular mechanism(s) underlying in the effects ... -
The Efficacy of Etoposide on H9c2 Cardiomyoblasts Against Doxorubicin Induced Cardiotoxicity
( OMICS International , 2015 , Article)Background: Doxorubicin (DOX), a widely used anticancer drug, has been associated with cardiotoxicity. Recently, DOX-induced cardiotoxicity has been attributed to topoisomerase II (TOPII)-β expression and activity. In our ... -
Comparison of the Protective Effects of Individual Components of Particulated trans-Sialidase (PTCTS), PTC and TS, against High Cholesterol Diet-Induced Atherosclerosis in Rabbits
( Hindawi Publishing Corporation , 2017 , Article)Previous studies showed the presence of Mycoplasma pneumoniae (M. pneumoniae) and membrane-shed microparticles (MPs) in vulnerable atherosclerotic plaques. H&S Science and Biotechnology developed PTCTS, composed by natural ... -
Characteristics of preferred walking patterns in young Qatari adults
( Qatar Foundation , 2016 , Conference Paper)Walking is the most natural and important activity of daily living as it refers to the primary type of terrestrial human locomotion. Analyses of gait patterns typically examine the speed and manner in which people prefer ... -
Inhibition of p90 ribosomal S6 kinase attenuates cell migration and proliferation of the human lung adenocarcinoma through phospho-GSK-3β and osteopontin
( Springer-Verlag , 2016 , Article)p90 ribosomal S6 kinase (p90RSK) constitutes a family of serine/threonine kinases that have been shown to be involved in cell proliferation of various malignancies via direct or indirect effects on the cell-cycle machinery. ... -
Na+/H+ exchanger isoform 1 induced osteopontin expression in cardiomyocytes involves NFAT3/Gata4
( Springer-Verlag , 2015 , Article)Osteopontin (OPN), a multifunctional glycophosphoprotein, has been reported to contribute to the development and progression of cardiac remodeling and hypertrophy. Cardiac-specific OPN knockout mice were protected against ... -
Oral PTCTS (Particulated Transialidase) Removes Serum Microparticles and Decreases Inflammation in Atherosclerotic Plaques of Rabbits
( Scientific Research Publishing , 2015 , Article)Background: Previous studies showed that atherosclerotic plaque vulnerability was related with microparticles (MPs)-vesicles larger than 100 nm, which released MMP9 collagenase. In our pre- vious study, intramuscular ... -
Heme oxygenase (HO)-1 induction prevents Endoplasmic Reticulum stress-mediated endothelial cell death and impaired angiogenic capacity
( Elsevier , 2016 , Article)Most of diabetic cardiovascular complications are attributed to endothelial dysfunction and impaired angiogenesis. Endoplasmic Reticulum (ER) and oxidative stresses were shown to play a pivotal role in the development of ... -
Nephroprotective Effects of Metformin in Diabetic Nephropathy
( Wiley , 2017 , Article)Metformin, a well-known anti-diabetic agent, is very effective in lowering blood glucose in patients with type 2 diabetes with minimal side-effects. Metformin is also being recommended in the treatment of obesity and ... -
Aldose Reductase as a Drug Target for Treatment of Diabetic Nephropathy: Promises and Challenges.
( Bentham Science Publishers , 2017 , Article)Diabetic nephropathy (DN) is one of the most serious microvascular complications of diabetes mellitus and the leading cause of end stage renal disease. One of the key pathways activated in DN is the polyol pathway, in which ... -
Role of pharmacists in the application of the transtheoretical model approach to enhance medication adherence in chronic diseases
( Society of Hospital Pharmacists of Australia , 2016 , Article)Adherence to prescribed medications is one of the most important aspects contributing to successful treatment. Medication adherence through self-management of chronic diseases is thought to be necessary to achieve improvements ... -
Bridging theory and practice: Mixed methods approach to instruction of law and ethics within the pharmaceutical sciences
( Elsevier , 2016 , Article)Background: Professional responsibilities are guided by laws and ethics that must be introduced and mastered within pharmaceutical sciences training. Instructional design to teaching typically introduces concepts in a ... -
Changes in student perceptions after a semester-long interprofessional education activity in Qatar
( Elsevier , 2016 , Article)Objectives Interprofessional education (IPE) is rapidly becoming integrated into university accreditation standards worldwide. However, the impact of IPE on student learning and practice is largely unknown in the Middle ... -
Important steps for introducing interprofessional education into health professional education
( Elsevier , 2016 , Article)Interprofessional education (IPE) engages students from different healthcare professions for learning with, from and about each other to improve collaboration and quality of care. Recognizing the complexity of designing ... -
Cross-national analysis of estimated narcotic utilization for twelve Arabic speaking countries in the Middle East
( Elsevier , 2016 , Article)Background: Access to narcotics has been described as suboptimal in the Middle East. The objectives of this study were to characterize estimated narcotic use in twelve Arabic-speaking nations and compare across world ... -
Diabetes Treatment Satisfaction Questionnaire – An Arabic adaptation for Qatar
( Elsevier , 2013 , Article)The Diabetes Treatment Satisfaction Questionnaire is recommended by the World Health Organization and the International Diabetes Federation for assessing diabetes care. We conducted a systematic linguistic adaptation of ... -
Validation of an Arabic version of the Diabetes Treatment Satisfaction Questionnaire in Qatar
( Elsevier , 2016 , Article)Aims: Several instruments evaluate patient-reported outcomes in diabetes mellitus (DM), but almost none are validated for use in Arabic language. The aim of this study is to test the psychometric properties and responsiveness ... -
The prevalence of novel psychoactive substances (NPS) use in non-clinical populations: a systematic review protocol
( BioMed Central , 2016 , Article)Background Novel psychoactive substances (NPS) are new narcotic or psychotropic drugs that are not controlled by the United Nations drug convention that may pose a serious public health threat due to their wide availability ... -
Implementation of An Ambulatory Pharmacist-Managed Anticoagulation Clinic In Qatar: Development of A New Service and A Pilot On Patients' Satisfaction and Quality of Life
( Elsevier , 2014 , Article)Objectives Pharmacist-managed anticoagulation clinics have been shown to improve the quality of life (QoL) of patients receiving anti-clot treatment. The first pharmacist-managed anticoagulation clinic in Qatar was ... -
Comparability of Interview and Self-Administration of the Functional Assessment of Chronic Illness Therapy-Tuberculosis (Facit-Tb) Instrument in Iraqi Pulmonary Tuberculosis Patients
( Elsevier , 2014 , Article)Objectives To investigate the extent to which two different modes of administration (interview by a trained interviewer versus self-administration) yielded a comparable estimate of health-related quality of life (HRQL) ...