College of Pharmacy: Recent submissions
Now showing items 981-1000 of 1280
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Suppression of GATA-3 increases adipogenesis, reduces inflammation and improves insulin sensitivity in 3T3L-1 preadipocytes
( Elsevier , 2020 , Article)© 2020 Impaired adipogenesis plays an important role in the development of obesity-associated insulin resistance and type 2 diabetes. Adipose tissue inflammation is a crucial mediator of this process. GATA-3 plays important ... -
Macroalgal polysaccharides in biomimetic nanodelivery systems
( Bentham Science Publishers , 2019 , Article Review)Background: Imitating nature in the design of bio-inspired drug delivery systems resulted in several success stories. However, the practical application of biomimicry is still largely unrealized owing to the fact that we ... -
Pharmaceutical pricing policies in Qatar and Lebanon: narrative review and document analysis
( Blackwell Publishing Ltd , 2019 , Article Review)Objectives: This study aimed at reviewing and analysing the pharmaceutical pricing policies implemented in two middle-east countries. Methods: Official documents related to national pharmaceutical pricing policies were ... -
Ibrutinib-associated sever skin toxicity: A case of multiple inflamed skin lesions and cellulitis in a 68-year-old male patient with relapsed chronic lymphocytic leukemia Case report and literature review
( SAGE Publications Ltd , 2019 , Article)Introduction: Ibrutinib is an oral inhibitor of Bruton's tyrosine kinase that is used for a variety of B cell hematological malignancies. Skin and subcutaneous tissue manifestations have been reported and were witnessed ... -
Preemptive Dose Adjustment Effect on the Quality of Anticoagulation Management in Warfarin Patients With Drug Interactions: A Retrospective Cohort Study
( SAGE Publications Inc. , 2019 , Article)One strategy to manage patients on warfarin starting an interacting drug is to increase the frequency of monitoring. Another strategy is to adjust warfarin dose around the time patient is started on an interacting medication, ... -
Maternal and perinatal outcomes and pharmacological management of Covid-19 infection in pregnancy: a systematic review protocol
( BMC , 2020 , Article)Over 4.2 million confirmed cases and more than 285,000 deaths, COVID-19 pandemic continues to harm significant number of people worldwide. Several studies have reported the impact of COVID-19 in general population; however, ... -
Inhibition of p90 ribosomal S6 kinase potentiates cisplatin activity in A549 human lung adenocarcinoma cells
( Wiley , 2020 , Article)© 2020 Royal Pharmaceutical Society Aim: Cisplatin is a standard treatment approach against lung adenocarcinoma. Resistance to cisplatin and the toxic side effects of cisplatin continue to remain a challenge. Combining ... -
Photopolymerization of Polymeric Composites in Drug Delivery, Tissue Engineering, and Other Biomedical Applications
( Springer , 2019 , Book chapter)Photopolymerization of polymeric composites has been widely used in several biomedical applications including, drug delivery, tissue engineering, and cell encapsulation as it combines the properties of both the photopolymerizable ... -
BIGIR at CLEF 2019: Automatic verification of Arabic claims over the web
( CEUR-WS , 2019 , Conference Paper)With the proliferation of fake news and its prevalent impact on democracy, journalism, and public opinions, manual fact-checkers become unscalable to the volume and speed of fake news propagation. Automatic fact-checkers ... -
Reactive and functionalized electrospun polymeric nanofibers for drug delivery and tissue engineering applications
( Future Medicine Ltd. , 2019 , Article)[No abstract available] -
Student and graduate perceptions regarding Canadian-based accreditation of a pharmacy program in Qatar
( American Association of Colleges of Pharmacy , 2019 , Article)Objective. To determine student and alumni perceptions of a Canadian-based pharmacy degree accreditation in a Middle Eastern setting and to explore the impact on patient care practices. Methods. Current and former Doctor ... -
The Effect of CYP2C19 and Nongenetic Factors on Clopidogrel Responsiveness in the MENA Region: A Systematic Review
( SAGE Publications Inc. , 2019 , Article Review)Clopidogrel is the cornerstone antiplatelet used in the treatment and prevention of thrombotic events. Some studies examined the effect of CYP2C19 polymorphism and nongenetic factors on clopidogrel response in the Middle ... -
Prescribers' perceptions of benefits and limitations of direct acting oral anticoagulants in non-valvular atrial fibrillation.
( Centro de Investigaciones y Publicaciones Farmaceuticas , 2020 , Article)There is an acknowledged lack of robust and rigorous research focusing on the perspectives of those prescribing direct acting oral anticoagulants (DOACs) for non-valvular atrial fibrillation (AF). The objective was to ... -
Pharmacy practice in the gulf states
( Elsevier , 2019 , Book chapter)The "Gulf States" are considered to represent the seven Arab countries bordering the Persian Gulf, namely, Bahrain, Iraq, Kuwait, Oman, Qatar, Saudi Arabia, and United Arab Emirates (UAE). The estimated regional population ... -
Evidence-based pharmacy practice research in low- and middle-income countries: Issues, challenges and synthesis
( Elsevier , 2019 , Book chapter)This chapter outlines the gaps in pharmacy practice research evidence in low- and middle-income countries (LMICs) using selected systematic reviews in pharmacy practice. Very few reviews dedicated to LMICs have been ... -
Management of neurological disorders and pharmacist's role: Multiple sclerosis
( Elsevier , 2019 , Book chapter)Multiple sclerosis (MS) is an autoimmune neurodegenerative disorder, characterized by chronic inflammation of the central nervous system. This paper focuses on the epidemiology, pathophysiology, etiology, and the risk ... -
A literature-based algorithm for the assessment, management, and monitoring of drug-induced QTc prolongation in the psychiatric population
( Dove Medical Press Ltd. , 2019 , Article Review)Background: Certain psychotropics and a number of other medications used to treat medical conditions in psychiatric patients can increase the risk of prolonging the corrected QT (QTc) interval on the electrocardiogram, ... -
The use of Socrative and Yammer online tools to promote interactive learning in pharmacy education
( Elsevier Inc. , 2019 , Article)Background and purpose Engagement of students in the didactic classroom setting restricts students’ time spent towards active learning, which in turn, adversely affects the retention of concepts taught through traditional ... -
A qualitative exploration of clozapine prescribing and monitoring practices in the Arabian Gulf countries
( Elsevier B.V. , 2019 , Article)Clozapine is considered as the first line antipsychotic for treatment resistant schizophrenia (TRS). Worldwide reports indicate an overall underutilization of clozapine in patients experiencing TRS. This study aims to ... -
EGFR Inhibitor Gefitinib Induces Cardiotoxicity through the Modulation of Cardiac PTEN/Akt/FoxO3a Pathway and Reactive Metabolites Formation: and Rat Studies.
( American Chemical Society , 2020 , Article)Gefitinib (GEF) is a selective inhibitor of the epidermal growth factor receptor (EGFR) used to treat non-small cell lung cancer. Yet, few cases of cardiotoxicity have been reported. However, the role of the PTEN/Akt/FoxO3a ...