Introduction: Breast cancer ranks as the most frequently diagnosed cancer globally, with the triple-negative breast cancer (TNBC) subtype linked to a notably poor prognosis. The absence of optimal therapeutic regimens ...

Introduction: Peganum harmala L. is a widely utilized plant in traditional medicine in many countries, including Qatar. Nevertheless, there have been several reports of toxic effects associated with the use of P. harmala ...

Ephedra foeminea Forssk, a widely distributed shrub in the East Mediterranean, possesses numerous traditional medicinal applications and is an abundant source of bioactive phytochemical metabolites. In this study, ult ...

Background: The Prosopis plant species have been reported for their diverse therapeutic benefits, including anti-inflammatory, anti-microbial, antioxidant, and anti- tumor properties. Prosopis cineraria, Prosopis ...

Background: Previous studies have investigated the association of rs1544410, rs7975232 and rs731236 polymorphisms on vitamin D receptor gene and its impact on diseases such as cancer, diabetes and hypertension in different ...

Ephedra foeminea Forssk., a Mediterranean shrub with diverse traditional medicinal applications, is rich in bioactive metabolites [1,2]. This study optimized the ultrasonic-assisted extraction (UAE) of phenolic and ...

There is a continuous global search for new anticancer agents from natural sources. In this study, the essential oils of Dittrichia viscosa (L.) Greuter leaves (DVEO) were extracted by hydrodistillation and chemically ...

Hypoxia plays a key role in cancer progression, mainly by stabilizing and activating hypoxia-inducible factor-1 (HIF-1) [1]. For HIF-1 to function under low oxygen conditions, it must interact with the transcriptional ...

Plant-derived metabolites have provided promising leads in the search for safer anticancer chemo-therapies. Among these, sesquiterpene lactones, predominantly present in the genus of the Aster-aceae family, exhibit great ...

Background and aims: In 2020 a global pandemic was declared caused by the severe acute respiratory syndrome coronavirus (SARS-CoV-2). The pandemic is still ongoing and continues to cause considerable mortality and morbidity ...