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Diagnostic Efficiency of Three Fully Automated Serology Assays and Their Correlation with a Novel Surrogate Virus Neutralization Test in Symptomatic and Asymptomatic SARS-COV-2 Individuals

Younes, Salma; Al-Jighefee, Hadeel; Shurrab, Farah; Al-Sadeq, Duaa W.; Younes, Nadin; ... more authors ... less authors ( MDPI , 2020 , Article)

Abstract: To support the deployment of serology assays for population screening during the COVID-19 pandemic, we compared the performance of three fully automated SARS-CoV-2 IgG assays: Mindray CL-900i® (target: spike [S] ...

Analytic comparison between three high-throughput commercial SARS-CoV-2 antibody assays reveals minor discrepancies in a high-incidence population

Nasrallah, Gheyath K; Dargham, Soha R; Shurrab, Farah; Al-Sadeq, Duaa W; Al-Jighefee, Hadeel; ... more authors ... less authors ( Nature Research , 2021 , Article)

Performance of three automated commercial serological IgG-based assays was investigated for assessing SARS-CoV-2 "ever" (past or current) infection in a population-based sample in a high exposure setting. PCR and serological ...

Draft Genome Sequence of an Extended-Spectrum β-Lactamase-Producing Klebsiella oxytoca Strain Bearing from Qatar.

Tsui, Clement K M; Sundararaju, Sathyavathi; Al Mana, Hassan; Hasan, Mohammad Rubayet; Tang, Patrick; ... more authors ... less authors ( American Society for Microbiology , 2020 , Article)

is an opportunistic human pathogen causing nosocomial infection. We report the draft genome of an extended-spectrum β-lactamase-producing isolate harboring an gene, a recently discovered colistin resistance analog, from ...

Detection of SARS-CoV-2 RNA by direct RT-qPCR on nasopharyngeal specimens without extraction of viral RNA.

Hasan, Mohammad Rubayet; Mirza, Faheem; Al-Hail, Hamad; Sundararaju, Sathyavathi; Xaba, Thabisile; ... more authors ... less authors ( Public Library of Science , 2020 , Article)

To circumvent the limited availability of RNA extraction reagents, we aimed to develop a protocol for direct RT-qPCR to detect SARS-CoV-2 in nasopharyngeal swabs without RNA extraction. Nasopharyngeal specimens positive ...

Molecular Characterization of Extended-Spectrum β-Lactamase-Producing and Among the Pediatric Population in Qatar

Perez-Lopez, Andres; Sundararaju, Sathyavathi; Al-Mana, Hassan; Tsui, Kin Ming; Hasan, Mohammad Rubayet; ... more authors ... less authors ( Frontiers Media , 2020 , Article)

Although extended-spectrum β-lactamase (ESBL)-producing Enterobacterales are a public health problem in the Arabian Peninsula, data on the molecular characteristic of their antimicrobial resistance determinants in children ...

Covid-19: Challenges & Perspectives

Al-Emadi, Talal; Bouras, Abdelaziz; Doi, Suhail; Tang, Patrick; Benslimane, Fatiha; ... more authors ... less authors ( College of Medicine - Qatar University , 2020 , Conference Program)

A Virtual Conference to shed light on the QU's prominent trends and research efforts addressing Corona virus.

Protection of Omicron sub-lineage infection against reinfection with another Omicron sub-lineage

Chemaitelly, Hiam; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; Yassine, Hadi M.; ... more authors ... less authors ( Nature Research , 2022 , Article)

There is significant genetic distance between SARS-CoV-2 Omicron (B.1.1.529) variant BA.1 and BA.2 sub-lineages. This study investigates immune protection of infection with one sub-lineage against reinfection with the other ...

Variations in respiratory syncytial virus activity following the relaxation of COVID-19 restrictions in Qatar.

Pérez-López, Andrés; Al Mana, Hassan; Iqbal, Muhammad; Suleiman, Mohammed; Hasan, Mohammad Rubayet; ... more authors ... less authors ( Oxford University Press , 2022 , Article)

Despite the relaxation of COVID-19 restrictions in Qatar in October-December 2020, the detection of RSV was reduced ∼25-fold compared with 2019. This dramatic decrease during the typical RSV season could be related to ...

Low-level amikacin resistance induced by AAC(6′)-Ib and AAC(6′)-Ib-cr in extended-spectrum β-lactamase (ESBL)-producing Enterobacterales isolated from urine in children

Hassan Al, Mana; Sundararaju, Sathyavathi; Eltai, Nahla O.; Al-Hadidi, Sara H.; Hasan, Mohammad Rubayet; ... more authors ... less authors ( Elsevier , 2021 , Other)

Amikacin is commonly used in children in combination with other agents as a last-resort treatment for severe infections caused by multidrug-resistant Gram-negative bacteria. Amikacin is also prescribed empirically in febrile ...

Effect of mRNA Vaccine Boosters against SARS-CoV-2 Omicron Infection in Qatar.

Abu-Raddad, Laith J; Chemaitelly, Hiam; Ayoub, Houssein H; AlMukdad, Sawsan; Yassine, Hadi M; ... more authors ... less authors ( Massachusetts Medical Society , 2022 , Article)

Waning of vaccine protection against coronavirus disease 2019 (Covid-19) and the emergence of the omicron (or B.1.1.529) variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have led to expedited ...