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Computational screening of known broad-spectrum antiviral small organic molecules for potential influenza HA stem inhibitors.

Mathew, Shilu; Al Thani, Asmaa A; Yassine, Hadi M ( Public Library of Science , 2018 , Article)

With the emergence of new influenza virus strains that are resistant to current inhibitors such as oseltamivir (anti-neuraminidase (NA)) and amantadine (anti-M2 proton channel), influenza A viruses continue to be a serious ...

Evolution and dynamics of the pandemic H1N1 influenza hemagglutinin protein from 2009 to 2017.

Al Khatib, Hebah A; Al Thani, Asmaa A; Yassine, Hadi M ( Springer Vienna , 2018 , Article)

The emergence of swine-origin pandemic H1N1 (pH1N1) in 2009 invigorated extensive surveillance programs worldwide which have resulted in the deposition of large numbers of H1N1 sequences to Genbank. In the present study, ...