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SARS-CoV-2 Infection and Smoking: What is the association? A brief review

Ishita, Gupta; Sohail, Muhammad Umar; Elzawawi, Khaled E.; Amarah, Ahmed H.; Vranic, Semir; ... more authors ... less authors ( Elsevier , 2021 , Article)

Susceptibility to severe illness from COVID-19 is anticipated to be associated with cigarette smoking as it aggravates the risk of cardiovascular and respiratory illness, including infections. This is particularly important ...

Detection of SARS-CoV-2 RNA by direct RT-qPCR on nasopharyngeal specimens without extraction of viral RNA.

Hasan, Mohammad Rubayet; Mirza, Faheem; Al-Hail, Hamad; Sundararaju, Sathyavathi; Xaba, Thabisile; ... more authors ... less authors ( Public Library of Science , 2020 , Article)

To circumvent the limited availability of RNA extraction reagents, we aimed to develop a protocol for direct RT-qPCR to detect SARS-CoV-2 in nasopharyngeal swabs without RNA extraction. Nasopharyngeal specimens positive ...

Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months

Laith J., Abu-Raddad; Chemaitelly, Hiam; Malek, Joel A.; Ahmed, Ayeda A.; Mohamoud, Yasmin A.; ... more authors ... less authors ( Elsevier , 2021 , Article)

We document two cases of viremic and prolonged active infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) where the viral genome was conserved for two months, but infection was with little or ...

Protection of Omicron sub-lineage infection against reinfection with another Omicron sub-lineage

Chemaitelly, Hiam; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; Yassine, Hadi M.; ... more authors ... less authors ( Nature Research , 2022 , Article)

There is significant genetic distance between SARS-CoV-2 Omicron (B.1.1.529) variant BA.1 and BA.2 sub-lineages. This study investigates immune protection of infection with one sub-lineage against reinfection with the other ...

Reporting of RT-PCR cycle threshold (Ct) values during the first wave of COVID-19 in Qatar improved result interpretation in clinical and public health settings

V. Coyle, Peter; Hassan Al Molawi, Naema; Ali Ben Hadj Kacem, Mohamed; Awni El Kahlout, Reham; Al Kuwari, Einas; ... more authors ... less authors ( Microbiology Society , 2022 , Article)

Introduction. The cycle threshold (Ct) value in real-time PCR (RT-PCR) is where a target-specific amplification signal becomes detectable and can infer viral load, risk of transmission and recovery. Use of Ct values in ...

Do preexisting antibodies against seasonal coronaviruses have a protective role against SARS-CoV-2 infections and impact on COVID-19 severity?

Gheyath K., Nasrallah ( Elsevier , 2022 , Other)

Because of the emergence of coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), many questions remain unresolved regarding the abundance of cross-reactivity ...

Prognostic tools and candidate drugs based on plasma proteomics of patients with severe COVID-19 complications

Al-Nesf, Maryam A. Y.; Abdesselem, Houari B.; Bensmail, Ilham; Ibrahim, Shahd; Saeed, Walaa A. H.; ... more authors ... less authors ( Nature Research , 2022 , Article)

COVID-19 complications still present a huge burden on healthcare systems and warrant predictive risk models to triage patients and inform early intervention. Here, we profile 893 plasma proteins from 50 severe and 50 ...

Antiviral activity of glucose-derived reactive metabolite, methylglyoxal against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

AlKhatib, Hebah A M; ElBashir, Israa; Yassine, Hadi M.; Thornalley, Paul J; Rabbani, Naila ( Hamad bin Khalifa University Press (HBKU Press) , 2022 , Article)

Background: The ongoing coronavirus disease 2019 (COVID-19) pandemic has resulted in a global health emergency. With incomplete vaccination and incomplete protection of the vaccinated population, there remains an urgent ...

Assessment of the Neutralizing Antibody Response of BNT162b2 and mRNA-1273 SARS-CoV-2 Vaccines in Naïve and Previously Infected Individuals: A Comparative Study

Shurrab, Farah M.; Al-Sadeq, Duaa W.; Abou-Saleh, Haissam; Al-Dewik, Nader; Elsharafi, Amira E.; ... more authors ... less authors ( MDPI , 2022 , Report)

The currently authorized mRNA COVID-19 vaccines, Pfizer-BNT162b2 and Moderna-mRNA-1273, offer great promise for reducing the spread of the COVID-19 by generating protective immunity against SARS-CoV-2. Recently, it was ...

Antibiotics Prescribing in Intensive Care Settings during the COVID-19 Era: A Systematic Review

Abu-Rub, Lubna; Abdelrahman, Hana A.; Johar, Al-Reem A; Alhussain, Hashim A.; Abdel Hadi, Hamad; ... more authors ... less authors ( MDPI , 2021 , Article)

The prevalence of patients admitted to intensive care units (ICUs) with SARS-CoV-2 infection who were prescribed antibiotics is undetermined and might contribute to the increased global antibiotic resistance. This ...

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