Browsing College of Health Sciences by Publication Date
Now showing items 121-140 of 1597
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Novel thiosemicarbazides induced apoptosis in human MCF-7 breast cancer cells via JNK signaling
( Taylor & Francis , 2015 , Article)In this study, novel thiosemicarbazides and 1,3,4-oxadiazoles were synthesized and evaluated for their anticancer effects on human MCF-7 breast cancer cell lines. Among the synthesized derivatives studied, compound ... -
Reference ranges of lymphocyte subsets in healthy Qatari adults
( Future Medicine Ltd , 2015 , Article)Aim: Determine reference ranges of lymphocyte subsets in healthy Qatari adults. Patients & Methods: Blood samples (n = 150) were investigated using four colors flow cytometery. Results: The mean percentage and absolute ... -
The distribution of Blastocystis subtypes in isolates from Qatar
( BioMed Central Ltd. , 2015 , Article)Background: Blastocystis is a common single-celled intestinal parasite of humans and other animals comprising at least 17 genetically distinct small subunit ribosomal RNA lineages (subtypes (STs)), nine of which have been ... -
Use of Germ-Free Animal Models in Microbiota-Related Research
( The Korean Society for Microbiology and Biotechnology , 2015 , Article)The large intestine is a home for trillions of microbiota, which confer many benefits on the host, including production of vitamins, absorption of nutrients, pathogen displacement, and development of the immune system. For ... -
First Study in Qatar to Reveal High Legionella Count in Cooling Towers
( Oxford University Press - ASCP , 2015 , Article)Legionella is an intracellular bacterium that can cause a severe communityacquired and nosocomial pneumonia, known as legionnaire disease (LD). The bacterium thrives in freshwater environments, including manmade water ... -
Pseudomonas aeruginosa: arsenal of resistance mechanisms, decades of changing resistance profiles, and future antimicrobial therapies.
( Future Medicine , 2015 , Article)Antimicrobial resistance is one of the most serious public health issues facing humans since the discovery of antimicrobial agents. The frequent, prolonged, and uncontrolled use of antimicrobial agents are major factors ... -
Durable immunity to oncogenic human papillomaviruses elicited by adjuvanted recombinant Adeno-associated virus-like particle immunogen displaying L2 17–36 epitopes
( Elsevier, Ltd , 2015 , Article)Vaccination with the minor capsid protein L2, notably the 17–36 neutralizing epitope, induces broadly protective antibodies, although the neutralizing titers attained in serum are substantially lower than for the licensed ... -
Evolution of the Web and its Uses in Healthcare
( American Society for Medical Technology , 2015 , Article)Before the Internet, people obtained health information from consulting a healthcare provider, books, magazines and newspapers or simply by asking family and friends. Nowadays, the internet has become a major source ... -
Patient-Physician Relationship and the Role of Clinical Decision Support Systems
( American Society for Medical Technology , 2015 , Article)In the last quarter of the twentieth century rapid development in the biological, medical, and pharmaceutical sciences has taken place and is continually developing causing a considerable broadening and deepening in the ... -
Health Informatics - Introduction
( American Society for Medical Technology , 2015 , Article)Health informatics is a wide-ranging science incorporating the complex mixture of people, organizations, illnesses, patient care and treatment. It is a scientific field that deals with the storage, retrieval, sharing, and ... -
A promising drug lead that inhibits HCV infectivity in a genotype-independent manner
( OMICS , 2015 , Conference Paper)E2 glycoprotein plays a significant role in the HCV life cycle, but only crystal structures of short peptides, or epitopes were present until Kong et al. resolved the new HCV E2 core (E2c) crystal structure. We have created ... -
A weight-management camp followed by weekly after-school lifestyle education sessions as an obesity intervention for Qatari children: a prospective cohort study
( Elsevier , 2015 , Conference Paper)Background Weight-management camp interventions for obese children are eff ective for short-term weight loss. However, there is little evidence indicating how gains made with such interventions can be maintained in the ... -
Microfluidics integrated biosensors: A leading technology towards lab-on-a-chip and sensing applications
( Multidisciplinary Digital Publishing Institute (MDPI) , 2015 , Article)A biosensor can be defined as a compact analytical device or unit incorporating a biological or biologically derived sensitive recognition element immobilized on a physicochemical transducer to measure one or more analytes. ... -
Detection and Phylogenetic Analysis of Human Pegivirus (GBV-C) Among Blood Donors and Patients Infected With Hepatitis B Virus (HBV) in Qatar
( Wiley , 2015 , Article)Human Pegivirus (HPgV), formerly GB virus-C/ Hepatitis G virus (GBV-C/HGV), collectively known as GBV-C, is widely spread and has been reported to be associated with non-A–E hepatitis. To our knowledge, no previous ... -
Myocardial ischemic subject's thymus fat: A novel source of multipotent stromal cells
( Public Library of Science , 2015 , Article)Objective Adipose Tissue Stromal Cells (ASCs) have important clinical applications in the regenerative medicine, cell replacement and gene therapies. Subcutaneous Adipose Tissue (SAT) is the most common source of these ... -
The Qatar Biobank: background and methods
( BioMed Central , 2015 , Article)Background: The Qatar Biobank aims to collect extensive lifestyle, clinical, and biological information from up to 60,000 men and women Qatari nationals and long-term residents (individuals living in the country for ≥15 ... -
Novel 1,5-diphenyl-6-substituted 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones induced apoptosis in RKO colon cancer cells
( Taylor & Francis , 2015 , Article)Novel 1,5-diphenyl-6-substituted-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones were synthesized and characterized. All compounds were screened for their anti-proliferative activities in five different cancer cell lines. The results ... -
Recent Perspective About the Amyloid Cascade Hypothesis and Stem Cell-Based Therapy in the Treatment of Alzheimer's Disease
( Bentham Science , 2016 , Book chapter)Alzheimer's disease (AD) is a complex neurodegenerative condition that is clinically characterized by impaired cognitive functions. The major morphologically observed lesion of AD encompasses the accumulation of extracellular ... -
Novel 1,5-diphenyl-6-substituted 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones induced apoptosis in RKO colon cancer cells
( Taylor and Francis Ltd , 2016 , Article)Novel 1,5-diphenyl-6-substituted-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones were synthesized and characterized. All compounds were screened for their anti-proliferative activities in five different cancer cell lines. The results ... -
Burden of diarrhea in the eastern mediterranean region, 1990-2013: Findings from the global burden of disease study 2013
( American Society of Tropical Medicine and Hygiene , 2016 , Article)Diarrheal diseases (DD) are leading causes of disease burden, death, and disability, especially in children in low-income settings. DD can also impact a child's potential livelihood through stunted physical growth, cognitive ...
