Browsing College of Health Sciences by Publication Date
Now showing items 181-200 of 1597
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Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals
( Nature Publishing Group , 2016 , Article)The liver is a key organ of metabolic homeostasis with functions that oscillate in response to food intake. Although liver and gut microbiome crosstalk has been reported, microbiome-mediated effects on peripheral circadian ... -
New 3-Cyano-2-Substituted Pyridines Induce Apoptosis in MCF 7 Breast Cancer Cells
( Multidisciplinary Digital Publishing Institute (MDPI) , 2016 , Article)The synthesis of new 3-cyano-2-substituted pyridines bearing various pharmacophores and functionalities at position 2 is described. The synthesized compounds were evaluated for their in vitro anti-cancer activities on five ... -
Macrophage Infection by Mycobacteria
( OMICS International , 2016 , Article)Mycobacterium tuberculosis is the etiological agent of tuberculosis. It is a pathogen that continues to draw international concerns particularly due to the emergence of multi-drug resistance and to the difficulties ... -
Frequency of Clinically Important RH and Kell Blood Group Antigens Among Blood Donors in Qatar
( HBKU Press , 2016 , Conference Paper)Background Very limited information is available about the prevalence of blood groups among Qatari population and residents. The information about frequencies of different blood group antigens is important to manage, ... -
Physico-chemical characterization of biochars from solid municipal waste for use in soil amendment
( Elsevier B.V. , 2016 , Article)The fast economic and demographic growth lead to generation of large amounts of solid wastes placing Qatar on top of most nations with a per capita solid waste generation of nearly 2.5 milliontons/year of which 60% is ... -
Quality of assessment and counselling offered by community pharmacists and medication sale without prescription to patients presenting with acute cardiac symptoms: a simulated client study
( Springer-Verlag , 2016 , Article)PURPOSE: Self-medication is common worldwide. However, the prevalence of sale of prescription medications without prescription and the quality of assessment and counselling provided by community pharmacists to cardiac ... -
Helminth infections among long-term residents and settled immigrants in Qatar in the decade from 2005 to 2014: temporal trends and varying prevalence among subjects from different regional origins
( BioMed Central , 2016 , Article)Background: Travel and migration from developing regions, where tropical diseases are common, to more developed industrialised nations can contribute to the introduction and subsequent spread of infections. With its rapidly ... -
Epidemiology of diabetic ketoacidosis in Arab patients with type 1 diabetes: a systematic review.
( Wiley , 2016 , Article)Diabetic ketoacidosis (DKA) is an acute and risky complication of type 1 diabetes. The aim of this study is to build the overall rate of DKA in Arab patients with type 1 diabetes in the 22 Arab nations. This is expected ... -
Metagenomic analysis demonstrates the diversity of the fecal virome in asymptomatic pigs in East Africa
( Springer Vienna , 2016 , Article)Pigs harbor a variety of viruses that are closely related to human viruses and are suspected to have zoonotic potential. Little is known about the presence of viruses in smallholder farms where pigs are in close contact ... -
Potential Nutrigenomic Approaches to Reduce the High Incidence of Obesity in Qatar
( OMICS International , 2016 , Article)Obesity prevalence has been growing exponentially over the last few decades, with a high impact in high-income countries, like Qatar. Several approaches are attempting to understand the causes of this phenomenon however ... -
Substances Secreted by Starved Human Dermal Fibroblasts Enhancing the Wound Healing Process in Rat without Scar: A Potential Acellular System for Wound Healing
( Hamad Bin Khalifa University Press , 2016 , Conference Paper)Background Despite being a major cellular component of various engineered skin substituent, underlying mechanism of successful fibroblast transplantation in wound healing is not clear. Here we show that substances derived ... -
Human c-MYBPC3 RNA Targeted Therapy, Reversal of Hypertrophic Cardiomyopathy in the Zebrafish Model
( Qscience. , 2016 , Conference Paper)Hypertrophic cardiomyopathy (HCM) is a serious heart disease and is defined as abnormal left ventricular (LV) wall thickening with diastolic dysfunction. HCM is an autosomal dominant monogenic disease caused by a mutation ... -
Assessment of morphological changes due to oxidative stress: leukodepleted packed red blood cells stored in SAGM
( Canadian Society of Transfusion Medicine , 2016 , Conference Paper)Background: In blood bank, the storage procedures of packed red blood cell (pRBC) require some conditions to ensure the maximum storage time for a safe blood supply. pRBC can be stored up to 42 days in 2-6⁰C, as long as ... -
Osteoporosis in patients with stroke: A cross-sectional study
( Medknow Publications , 2016 , Article)Stroke-related impairments and inactivity contribute to the accelerated development of bone mass removal. However, the extent of decrease in bone mineral density (BMD) after stroke and all factors that influence such rapid ... -
Level of physical activity in patients with osteoporosis
( Springer London , 2016 , Conference Paper)Objectives: The aim of this research was to examine the degree and types of physical activity (heavy physical activity, medium heavy and light physical activity) in female patients with lower bone mineral density compared ... -
Vitamin d deficiency and bone density in patients after stroke
( Springer Verlag , 2016 , Conference Paper)Introduction: Vitamin D deficiency and osteoporosis are highly prevalent among stroke patients. The adverse effects of vitamin D deficiency on bone metabolism seem to be aggravated by immobilization of paretic extremities. ... -
Inflammogenesis of Secondary Spinal Cord Injury
( Frontiers Media , 2016 , Article)Spinal cord injury (SCI) and spinal infarction lead to neurological complications and eventually to paraplegia or quadriplegia. These extremely debilitating conditions are major contributors to morbidity. Our understanding ... -
Genetic Epidemiology of Type 1 Diabetes in the 22 Arab Countries.
( Current Medicine Group , 2016 , Article)Type 1 diabetes (T1D) is a complex autoimmune disorder that results from the T cell-mediated destruction of the pancreatic β cells and is due to interactions between environmental and genetic factors. Although Arabs have ... -
Study protocol: Mother and Infant Nutritional Assessment (MINA) cohort study in Qatar and Lebanon
( BioMed Central , 2016 , Article)Background The Middle East and North Africa region harbors significant proportions of stunting and wasting coupled with surging rates of non-communicable diseases (NCDs). Recent evidence identified nutrition during the ... -
Dietary patterns and colorectal cancer
( Elsevier , 2016 , Article)Summary Background & aimsDietary pattern and lifestyle have been reported to be important risk factors in the development of colorectal cancer (CRC). However, the mechanism of action of dietary factors in CRC disease is ...