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Bidirectional communication between the Aryl hydrocarbon Receptor (AhR) and the microbiome tunes host metabolism
(
Nature Publishing Group in partnership with Nanyang Technological University
, 2016 , Article)
The ligand-induced transcription factor, aryl hydrocarbon receptor (AhR) is known for its capacity to tune adaptive immunity and xenobiotic metabolism-biological properties subject to regulation by the indigenous microbiome. ...
Zebrafish larvae as a model to demonstrate secondary iron overload.
(
Wiley
, 2018 , Article)
Thalassemia is the most common genetically inherited blood disorder arising from a defect in hemoglobin production, resulting in ineffective erythropoiesis and severe hemolytic anemia. While transfusion therapy corrects ...
Burden of disease attributable to suboptimal diet, metabolic risks and low physical activity in Ethiopia and comparison with Eastern sub-Saharan African countries, 1990-2015: findings from the Global Burden of Disease Study 2015.
(
BioMed Central
, 2018 , Article)
Twelve of the 17 Sustainable Development Goals (SDGs) are related to malnutrition (both under- and overnutrition), other behavioral, and metabolic risk factors. However, comparative evidence on the impact of behavioral and ...
Nanodiagnostics for tuberculosis detection
(
Taylor & Francis
, 2017 , Article)
Introduction
Tuberculosis (TB) is a leading killer worldwide. End TB strategy aims at ending the TB epidemic by 2030. Early, accurate, and affordable diagnosis represents a cornerstone to achieve this goal. Innovative ...
The effect of protein supplementation on body muscle mass and fat mass in post-bariatric surgery: a randomized controlled trial (RCT) study protocol.
(
BioMed Central
, 2018 , Article)
Severe weight loss through means of bariatric surgery has been associated with loss of muscle mass due to lack of absorption of protein. The aim of this RCT is to investigate the effectiveness of protein supplementation ...
General practitioner use of a C-reactive protein point-of-care test to help target antibiotic prescribing in patients with acute exacerbations of chronic obstructive pulmonary disease (the PACE study): study protocol for a randomised controlled trial.
(
BioMed Central
, 2017 , Article)
Most patients presenting with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in primary care are prescribed an antibiotic, which may not always be appropriate and may cause harm. C-reactive protein ...
Combine iron Chelation therapy ameliorates decline of iron on iron loaded Zebrafish embryo
(2017 , Conference Proceedings)
Thalassemia is the most common genetically inherited blood disorder in the world arisen
from defect in hemoglobin production, resulting in ineffective erythropoiesis and rapid destruction
of RBC in the periphery that ...
Iron shuttle chelation therapy enhances to reduce misplaced iron on secondary iron overloaded adult zebrafish
(2017 , Conference Paper)
Thalassemia is the most common genetically inherited blood disorder in the world arises from defect in hemoglobin
production, results in ineffective erythropoiesis and the rapid destruction of RBC in the periphery that ...
Cellular immune activation in Sardinian middle-aged, older adults and centenarians
(
Elsevier
, 2017 , Article)
In addition to viral infections, malignant disorders, autoimmune diseases, and allograft rejection episodes, neopterin increases in older people where it is found to be predictive of overall mortality. Thus, the serum ...
Gut microbial communities modulating brain development and function
(
Taylor & Francis
, 2012 , Article)
Mammalian brain development is initiated in utero and internal and external environmental signals can affect this process all the way until adulthood. Recent observations suggest that one such external cue is the indigenous ...