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A profound computational study to prioritize the disease-causing mutations in PRPS1 gene.
(
Springer Verlag
, 2017 , Article)
Charcot-Marie-Tooth disease (CMT) is one of the most commonly inherited congenital neurological disorders, affecting approximately 1 in 2500 in the US. About 80 genes were found to be in association with CMT. The phosphoribosyl ...
Novel mutation in an Egyptian patient with infantile Canavan disease.
(
Springer Verlag (Germany)
, 2016 , Article)
Canavan disease (CD) is a rare fatal childhood neurological autosomal recessive genetic disease caused by mutations in the ASPA gene, which lead to catalytic deficiency of the ASPA enzyme that catalyzes the deacetylation ...
A review of climate change in South East Asian Countries and human health: Impacts, vulnerability, adaptation, and mitigation
(
World Health Organization
, 2016 , Article)
Climate Change (CC) is one of the most significant global environmental challenges humanity has faced. The most dominant causative factors due to human activity are emissions of greenhouse-gasses (GHG) from the combustion ...
CD146, a novel target of CD44-signaling, suppresses breast tumor cell invasion.
(2017 , Article)
We have previously validated three novel CD44-downstream positively regulated transcriptional targets, including Cortactin, Survivin and TGF-β2, and further characterized the players underlying their separate signaling ...
P3. 210 Estimating the antibody prevalence of herpes simplex virus type 2 among select middle east and north africa populations
(
BMJ Publishing Group
, 2017 , Conference Proceedings)
Introduction There are very limited data on herpes simplex virus type 2 (HSV-2) infection in the Middle East and North Africa (MENA). We examined the overall and age-specific HSV-2 antibody prevalence among select MENA ...
Structural modeling of p.V31F variant in the aspartoacylase gene.
(
Springer Verlag
, 2016 , Article)
Aspartoacylase (ASPA) is an abundant enzyme in the brain, which catalyzes the conversion of N-acetylaspartate into acetate and aspartate, deficiency in its activity leads to degeneration of the white matter of the brain ...
Role of nutrition in oral and pharyngeal cancers: From etiology to prevention
(
Springer, Cham
, 2017 , Book chapter)
Oral and pharyngeal cancers (OPC) are highly prevalent tumors and rank as the sixth most common neoplasms. Some dietary factors have been linked to increased risk of OPC such as consumption of red meats and saturated fats, ...
Dietary patterns and the risk of coronary heart disease among Jordanians: A caseecontrol study
(
Elsevier
, 2017 , Article)
Background and Aims
Dietary pattern and lifestyle have been reported to be significant risk factors in the development of coronary heart diseases (CHD). The contribution degree of these dietary risk factors in CHD ...
Propionic acidemia in the Arab World.
(
Elsevier
, 2015 , Article)
The autosomal recessive disease propionic acidemia (PA) is an inborn error of metabolism with highly variable clinical manifestations, caused by a deficiency of propionyl-CoA carboxylase (PCC) enzyme, due to mutations in ...
Nature and delivery of cardiac rehabilitation in New Zealand: Are services equitable to other high-income countries?
(
New Zealand Medical Association
, 2019 , Article)
Aims: To compare the nature and delivery of cardiac rehabilitation (CR) services within New Zealand by island (North vs South; NI, SI), and to other high-income countries (HICs).
Methods: In this cross-sectional study, ...